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Suspension For The Obstructive Sleepapnea Hypopnea Syndrome With Glossoptosis

Posted on:2020-12-26Degree:MasterType:Thesis
Country:ChinaCandidate:D JiFull Text:PDF
GTID:2404330590480201Subject:Clinical medicine
Abstract/Summary:PDF Full Text Request
Objective To assess the efficacy of the Soft Palate Surgeries with Hyoid Bone Suspension for obstructive sleep apnea hypopnea syndrome(OSAHS)with glossoptosis.Methods An electronic search was Conducted in VIP,CNKI,and Pubmed databases.Studies were included according to inclusion and exclusion criteria.Literature quality was evaluated by MINORS.Effects of Soft Palate Surgeries with Hyoid Bone Suspension on patients were qualitatively evaluated,and meta-analyzed by RevMan 5.3.Results A total of 13 self-controlled trials or RCTs involving 310patients were finally included.Meta-analyses showed a significant improvement in apnea hypopnea index(AHI)、respiratory disturbance index(RDI)、lowest arterial oxygen saturation(LSaO2),[AHI 45.61,95%CI(42.48,48.73),P<0.00001],[RDI 35.26,95%CI(22.47,48.04),P<0.00001],[LSaO2-20.16,95%CI(-24.99,-15.33),P<0.00001].Significant heterogeneity existed in Meta analysis and Sensitivity analysis indicated that Lin Ling’s result might be the cause.Conclusion A larger sample size、high-quality studies as well as objective indicators for the evaluation of obstructive sites are still needed.The Soft Palate Surgeries with Hyoid Bone Suspension are effective in reducing AHI、RDI and enhancing LSaO2,but more evidences are warranted for its effects.The long-term efficacy remains to be studied.
Keywords/Search Tags:Obstructive sleep apnea hypopnea syndrome, Hyoid Bone Suspension, Meta analysis, Systematic review
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