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Relationship Between Normal Body Mass Index And Obesity OSA And Dyslipidemia

Posted on:2020-08-24Degree:MasterType:Thesis
Country:ChinaCandidate:F ZhangFull Text:PDF
GTID:2404330590455977Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Objective:To explore the relationship between normal body mass index and obese OSA and dyslipidemia,and provide ideas for the prevention and treatment of different types of OSA.Methods:A case-control study was conducted to collect patients with snoring in the presence of polysomnography(PSG)in the Department of Geriatrics,First Hospital of Shanxi Medical University from January 2015 to December 2017,collecting relevant medical history data,blood biochemical indicators,and more.Guide sleep monitoring results.According to the level of blood lipids,the patients were divided into dyslipidemia group and normal blood lipid group,and the influencing factors of dyslipidemia were analyzed.According to the difference of body mass index,the patients were divided into normal body reorganization and overweight(obesity)group.The general data and blood lipid levels of OSA patients and control group were compared between the two groups.Multivariate logistic regression analysis was used to identify the relationship between blood lipids anomalies and OSA in OSA patients with different BMI.Results:1.The age,weight,AHI,and BMI of the patients were different in the dyslipidemiaand normal blood lipid levels,P<0.05.2.Multivariate logistic regression analysis showed that BMI(OR=1.190,95% CI:1.055-1.343)and AHI(OR=1.075,95% CI: 1.021-1.132)were risk factors for dyslipidemia.3.Compared with normal weight + simple snoring,the normal body weight + OSA HDL-C level was lower(P <0.05);there was no statistical difference between overweight(obesity)+ OSA and overweight(obesity)+ simple snoring.Learning meaning.4.Normal weight OSA group AHI(OR=1.376,95% CI: 1.091-1.735)was a risk factor for dyslipidemia;in the overweight(obese)OSA group,AHI was not associated with the risk of dyslipidemia.Conclusion:Both obesity and OSA are associated with dyslipidemia.In normal-weight OSA patients,OSA is associated with dyslipidemia;in OSA patients with obesity,no OSA is associated with abnormal blood lipid levels.
Keywords/Search Tags:Obstructive sleep apnea syndrome(OSA), Lipid metabolism, Body mass index(BMI)
PDF Full Text Request
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