Retrospective Analysis Reveals The Risk Factors Correlated To The Formation Of Ventricular Aneurysm In Patients With ST-segment Elevation Myocardial Infarction

Objective: To explore the related factors of ventricular aneurysm formation in patients with ST-segment elevation myocardial infarction(STEMI).Methods: A total of 1,030 STEMI patients were admitted to 900 Hospital of the Joint Logistics Team from January 2007 to December 2017.Seventy patients without coronary angiography or incomplete data were excluded,and 960 patients were finally included.According to the occurrence of left ventricular aneurysm(LVA),the individuals were divided into the LVA group(n=99)and the non-ventricular aneurysm group(non-LVA group,n=861).The characteristics,including age,gender,body mass index(BMI),hypertension,hyperlipidemia,diabetes,smoking,previous angina pectoris,primary percutaneous coronary intervention(PPCI),anterior wall myocardial infarction,preoperative TIMI grading,hypersensitive C-reactive protein(hs-CRP),brain natriuretic peptide(BNP),creatine kinase(CK),creatine kinase-myocardial band(CK-MB),Preoperative troponin and medications,were compared between the two groups.Results: The incidence of LVA was 10.3% among 960 STEMI patients.In the multivariate logistic regression model,the results showed that anterior wall myocardial infarction,LAD/LM as the infarction related artery,postoperative hs-crp > 8 mg/L,postoperative BNP > 100pg/m L,CK peak,CKMB peak,postoperative LVEF < 55%,previous history of angina pectoris,emergency PCI,and ST resolution≥50% at 2 hours were independently correlated with the occurrence of LVA after STEMI,OR values were:1.40,4.765,2.948,2.547,1.000,1.004,4.571,0.044,0.270,0.002.Conclusion: 1.In this study,the incidence of LVA in STEMI patients was 10.3%.2.Anterior wall myocardial infarction,LAD/LM as the infarction related artery,postoperative hs-CRP>8mg/L,postoperative BNP > 100pg/m L,CK peak,CKMB peak,postoperative LVEF < 55%,previous history of angina pectoris,emergency PCI,previous angina pectoris and ST resolution≥50% at 2 hours was a strong correlation factor for the occurrence of LVA after STEMI,and Anterior wall myocardial infarction,LAD/LM as the infarction related artery,postoperative hs-CRP>8mg/L,postoperative BNP > 100pg/m L,CK peak,CKMB peak,postoperative LVEF < 55% was positively correlated with the occurrence of LVA.However,previous angina pectoris,emergency PCI and ST resolution≥50% at 2 hours were negatively correlated with the occurrence of LVA.