Objective:With the method of prospective study,using data mining method,analysis summary professor Wang Xixing treatment of breast cancer clinical core thought and drug laws,provide objective basis for further guide clinical syndrome differentiationMethods:According to the cases included in the standard screening in November2017 to December 2018,professor Wang Xixing personally make a diagnosis and give treatment of breast cancer outpatient cases,the maximum expected value algorithm,using frequency analysis method,summarizes the general information of patients with breast cancer,main symptoms and main Wang Xixing professor of treatment of breast cancer drugs,prescription and drugs;EM clustering method was used to summarize the differentiation and classification of breast cancer.PCA principal component principal component analysis was used to summarize the main symptoms of each type of syndrome,and then the main points of syndrome differentiation were obtained.FPGrowth association analysis was used to analyze and summarize common drug combinations.Results:1.Syndrome rules: four common syndromes of breast cancer are summarized by EM clustering: liver and kidney Yin deficiency syndrome(31%),liver and spleen dysregulation syndrome(21%),liver and gallbladder disharmony syndrome(20%),liver and spleen deficiency syndrome(13%).2.Key points of syndrome differentiation: the PCA principal component analysis method was used to summarize the key points of syndrome differentiation of 4 common types of breast cancer.Yin deficiency syndrome of liver and kidney: insomnia,low back pain,night sweats,irritability,hot flashes,red tongue,little moss,fine pulse.Do not adjust card: not mei,be agitated,defecate is difficult,breast bilge painful,inappetence,tongue is red,moss is thin,pulse string.Syndrome of disharmony between liver and gallbladder: chest tightness,vomiting,thirsty mouth,loss of appetite,bitter mouth,red tongue,yellow greasy moss,smooth pulse.Liver and spleen deficiency: fatigue,loose stools,loss of appetite,dizziness,shortnessof breath,pink tongue,thin moss,heavy pulse.3.Relationship between party a and party b:Yin deficiency syndrome of liver and kidney,to kidney-tonifying liver,side with zishui qinggan drink plus or minus.Disharmony of liver and spleen syndrome,to dredge liver jianpi,fang xiaoyaosan plus or minus.Hepatobiliary disharmony syndrome,to dredge liver and gallbladder,with small chaihu decoction and temperature gallbladder decoction plus reduction.For the deficiency of liver and spleen,nourishing the liver is used to strengthen the spleen.5.Medication rules: 80 drugs are commonly used,and the top 30 drugs in frequency of use are: fritillary bulb of zhejiang,shanci mushroom,bupleurum chinense,white peony root,angelica sinensis,pinellia ternata,tianlong,poria cocos,peony peel,orange peel,etc.The most frequently used drugs were warm ones,and the most frequently used drugs were bitter,bitter and sweet ones.Treatment and disease commonly used drug combinations are three out of 11 arrises-rhizoma zedoariae,dragon mountain arrowhead-zhejiang fritillary,fructus ligustri lucidi-ink dry lotus,lotus leaf-snake tongue grass-hill,arrowhead,fresh mushroom lily-black nightshade,dwarf lilyturf,fructus schisandrae,keel-oysters,rhizoma anemarrhenae,cortex phellodendri,stone calamus-polygala-tuber fleeceflower stem,turmeric,zedoary,rhizoma drynariae,malaytea scurfpea fruit.Conclusion : From Wang Xixing clinical medication analysis,fully embodies the teacher wang treatment is given priority to with liver,breast cancer treated from liver,whole attention to reconcile viscera,harmonize qi and blood,supporting,fever and,embodies the "and" the core idea of cure. |