The Effect Of Early Postoperative Recovery In Patients With Intercostal Nerve Block Combined With Flurbiprofen Ester In Single Utility Port Video-assisted Thoracoscopic Surgery With Lung Cancer

Objective:To observe the early postoperative recovery,like postoperative analgesia,inflammatory reaction and postoperative complications,about the application of intercostal nerve block combined with flurbiprofen ester in single utility port video-assisted thoracoscopic surgery patients with lung cancer.Methods:Ninety-five patients with lung cancer were selected,which were performed single utility port video-assisted thoracoscopic surgery.Then they were divided into two groups,according to the application of intercostal nerve block or not:intercostal nerve block combined with flurbiprofen ester group(B group),group of flurbiprofen ester used alone(F group).Before closing thoracic incision after surgery,the patients in B group were injected with 0.75%ropivacaine 10ml to two incisions,with thoracoscopic.The two groups were consistent with the same anesthesia.The patients in both of these two groups were injected with 10mg flurbiprofen ester twice a day after the surgery.Then recorded VAS score of two groups 6h,12h,24h,48h,72h after the operation respectively.Recorded the preoperative and postoperative CRP and compared the difference of CRP between two groups,recorded the rate of postoperative complications such as pulmonary infection,pulmonary atelectasis,pleural effusion.Compared the difference of drainage volume,chest drainage duration,postoperative stay and the time of rescue analgesia between two groups.Results:Forty-four patients were in B group,and fifty-one patients were in F group.Compared with the F group,B group’s VAS score at 6h,12h,24h were significantly lower(P<0.05),there is no difference of VAS score at 48h,72h between two groups.Meanwhile,the VAS score of B group has obvious uptrend between 6h to 24h after surgery.The postoperative CRP of both two groups were obviously higher than preoperative(P<0.05),but there is no difference of the perioperative CRP’s change between two groups(P>0.05).The rate of postoperative complications,drainage volume,chest drainage duration and postoperative stay are fewer than F group.As for the time of rescue analgesia,there is no difference between two groups.Conclusion:Compared with flurbiprofen ester used alone,intercostal nerve block combined with flurbiprofen ester had less pain degree for the patients with lung cancer after single utility port video-assisted thoracoscopic surgery,and reduced the rate of postoperative complications,drainage volume,chest drainage duration and postoperative hospital stay.But it had no significant influence on inflammatory reaction after single utility port video-assisted thoracoscopic surgery,it was limited in continuous analgesia after the surgery.