| Objective: Application of three-dimensional speckle tracking technology for left ventricular torsion and strain parameters during lung cancer chemotherapy,discusses the technology application in myocardial toxicity assessment of lung cancer chemotherapy correlation value.Methods: Two groups of patients were pre-established.One group was 51 patients in the experimental group.The patients were randomly selected from non-small cell lung cancer combined with chemotherapy.The other group was 30 patients in the control group.The healthy population was randomly selected and the above two groups were obtained.LVEF,left ventricular strain and torsion related indicators were monitored and monitored for statistical analysis to assess the diagnostic efficacy of myocardial toxicity.RESULTS: During the course of chemotherapy,the myocardial strain and torsion indexes of lung cancer patients gradually decreased with the increase of treatment time,and the changes in the three time intervals before chemotherapy,3 cycles after chemotherapy and 6 cycles after chemotherapy were all changed.has statistical significane.The area under the LVPtw curve is 0.769,which is the highest diagnostic performance indicator with a sensitivity of 87% and a specificity of 57%.The area under the LVTor curve is 0.714 and the area under the LVLLS curve is 0.707.Conclusion: 3D-STI technique is used to obtain three indexes of LVGLS,LVPtw and LVTor,which are representative of myocardial strain and torsion related parameters.It has certain clinical decision-making significance for subclinical myocardial toxicity caused by chemotherapy drugs in chemotherapy course. |
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