A Comparative Analysis Of The Diagnosis And Treatment Trends Of Acute Coronary Syndrome From 2008 To 2015

Objective:To evaluate the trends of the clinical characteristics,diagnosis and treatment pattrens anrdotcomes of acute coronary syndrome(ACS)patients in the cardiovascular center of the first hoapital of jilin university from 2008 to2015.Method:Collet the first 5 case of acute st-elevation myocardial infarction STEMI and the first 5 cases of acute non-st-elevation myocardial infarction(NSTEMI)and unstable angina pectoris(UA)were collected from the cardiovasoular center of the first hoapital of jilin university from January 1,2008 to December31,2015.clinical information is provided and analyzed as a case study.Results:from 2008-2015,There were 932 cases in total Cases of coronary artery syndrome were included in study.The median age of the patients decreased from 65 to 61 years(P=0.045).The value of muscle unitary decreased from82.70 to 70.85(P=0.002).The proportion of patients with a history of hypertension increased from 49.2% to 59.5%(P=0.024),and the patients with a clear history of coronary heart disease increased from 17.5% to 32.3%(P<0.001)Treatment:The proportion of patients with acute st-segment elevation myocardial infarction(STEMI)receiving direct percutaneous arteriaintervention(PCI)increased from 68.10% to 72.20%.Within 2 hours after admission,the utilization rate of P2Y2 receptor antagonist increaed from 21.30% to 30.40%(P=0.002),and there was no significant improvement in the application of B receptor blocker and ACEI/ARB.The outcome of patients in hosptial: The incidence of severe heart failure in hosptial was 9.60% to 4.60%(P=0.023)(2)The incidence of nosocomial severe arrhythmias decreased from 15% to 4.60%(P=0.023)(3)The incidence of nosocomial hermorrhage decreased from 2.90%to 0.4%(P=0.011)There was no statistically significant difference in the changes of nosocomial mortality of patients discharged within 2 years was15.47%,10.89%,and 10.34%,respectively,and the all-cause mortality within 2years after discharge was 15.47%,10.89% and 10.34%,respectively.(conclusion)from 2008 to 2015,the age of patients with acute coronary syndrome in the cardiovascular Center of the first hospital of jilin universitytended to be younger.The proportion of patients with a history of hypertension and coronary heart disease had increased.The propotion of STEMI patients receiving PCI treatment is gradually increasing.and the use of P2Y2 receptor antagonist and IIb IIIa glycoprotein receptor antagonist is gradually increasing.and the use of P2Y2 receptor antagonist and IIb IIIa glycoprotein receptor antagonist is gradually increasing.However,there are still insufficient use of B receptor blockersand ACEI/ARB drugs that can definitely.Reduce the mortality,and the overall diagnosis and treatment situation is still different from the guidelines.Nosocomial mortality was not improved,but the incidence of severe heart failure,severe arrhythmia and bleeding during hospitalization declined.