Study On The Effect Of Hope And Symptom Burden On Quality Of Life Based On The Theory Of Unpleasant Symptoms In Patients With Breast Cancer Chemotherapy

Objective:Understand the status of breast cancer chemotherapy patients’ hope,symptom burden and quality of life;analyze the factors affecting the hope and symptom burden of breast cancer chemotherapy patients;explore the relationship between breast cancer chemotherapy patients’ hope,symptom burden and quality of life.Methods: A convenient sampling method was used to select breast cancer chemotherapy patients from two tertiary hospitals in Changchun City.From November 2017 to June 2018,a questionnaire survey was conducted on 442 breast cancer chemotherapy patients who met the inclusion and exclusion criteria.The survey tool consists of four parts: a general data questionnaire,a Herth hope index scale,a memorial symptom assessment scale,and a functional assessment of cancer therapy-breast quality of life instrument.Statistical analysis of the general data of patients with breast cancer chemotherapy using frequency and composition ratios;median and quartiles were used to describe the status of hope,symptom burden and quality of life;using Mann-Whitney U test and Kruskal-Wallis H test to analyze the demographic differences in the hope and symptom burden of breast cancer chemotherapy patients;to analyze the factors affecting the hope and symptom burden of breast cancer chemotherapy patients by multivariate stepwise regression analysis and decision tree analysis;to explore the breast cancer chemotherapy patients by Spearman correlation analysis the relationship those hope,symptom burden and quality of life.Results: 1.The median score for breast cancer chemotherapy patients hope is 29.00,the median score for symptom burden is 0.44,and the median score for quality of life is 65.08.2.The differences in the hope scores of different ages,marital status,education level,place of residence,working status,occupation,average monthly household income,type of medical insurance,religious belief,tumor stage,medication cycle and breast cancer family history are statistics academic significance(P <0.05).3.The differences in the symptom burden scores of different education levels,residence,working status,occupation,average monthly household income,medical insurance type,religious belief,medication cycle and chemotherapy type are statistics academic significance(P < 0.05).4.The total score of breast cancer chemotherapy patients’ hope,the temporality and futrue,the positive readiness and expectancy,the interconnectedness and the total score of symptom burden,the physical symptom distress score,the psychological symptom distress score,the global distress index were significantly negatively correlated(P <0.05).5.The total score of breast cancer chemotherapy patients’ hope,the temporality and futrue,the positive readiness and expectancy,the interconnectedness and the total quality of life,the physical,the social/family,the emotional,the functional,the additional concerns are significantly positively correlated(P < 0.05).6.The total score of symptom burden,the physical,the social/family,the emotional,the functional and the additional concerns of breast cancer chemotherapy patients are significantly negatively correlated(P <0.05).Conclusions: 1.The hope,symptom burden and quality of life of breast cancer chemotherapy patients are at a medium level.2.The age,marital status,education level,place of residence,working status,occupation,average monthly household income,type of medical insurance,religiousbelief,tumor stage,medication cycle,family history of breast cancer are the influencing factors of hope of breast cancer chemotherapy patients.3.The education level,place of residence,working status,occupation,average monthly household income,type of medical insurance,religious belief,medication cycle,and type of chemotherapy are the influencing factors of symptom burden of breast cancer chemotherapy patients.4.The hope of breast cancer chemotherapy patients is significantly negatively correlated with the symptom burden,and is significantly positively correlated with quality of life.The symptom burden of breast cancer chemotherapy patients is significantly negatively correlated with quality of life.