Long-Term Quality Of Life After Buccal Cancer Surgery And Its Influencing Factors

ObjectiveTo investigate the changes of quality of life（QOL）in patients with buccal carcinoma 5years after operation,and to investigate the influencing factors of QOL in patients with buccal carcinoma after operation.The quality of life evaluation was introduced into the selection of clinical treatment methods and the evaluation of treatment effects for buccal cancer,so as to explore the best surgical methods and provide scientific basis for the treatment and improvement of buccal cancerMethodsA retrospective analysis in March 2010 to March 2012 in the first affiliated hospital of Zhengzhou University surgical treated 61 cases of oral and maxillofacial tumors by pathological diagnosis of buccal carcinoma preoperative clinical data,with the University of Washington quality of life questionnaire（University of Washington quality of life questionnaire,UW-QOL）5 years postoperatively in patients with the fourth edition of quality of life（QOL）quality of life,the possible factors affecting the quality of survival to statistics.ResultsThe relevant factors in the questionnaire included patients’gender,age,education level,tumor site,cervical lymph node dissection,tumor T stage,tumor N stage,smoking,postoperative radiotherapy,postoperative chemotherapy,marital status,skin flap repair selection,and depth of infiltration.The total QOL score of men was 883.3,while that of women was 914.5,with no significant difference（P>0.05）.The total QOL score was 872.6for age<40,890.3 for age 40-60,and 884.2 for age>60,with no significant difference（P>0.05）.Below secondary education level,the total QOL score was 820.7,and the total QOL score for higher education was 886.4,with no significant difference（P>0.05）.The QOL total score was 830.6 when the tumor was located in the front and middle part,and 842.4 when the tumor was located in the back part,with no significant difference（P>0.05）.The total score of functional neck dissection was 887.5.The total QOL score of patients undergoing radical neck dissection was 813.2,and the difference was statistically significant（P<0.05）.The total QOL score of T stage（T₁+T₂）was 946.2,and the total QOL score of T stage（T₃+T₄）was842.8,with statistical difference（P<0.05）.The total QOL score of tumor N stage（N₀+N₁）was 874.5,and the total QOL score of tumor N stage（N₂+N₃）was 774.8,with statistical difference（P<0.05）.The total QOL score of smokers was 818.1 and that of non-smokers was927.9,with statistical difference（P<0.05）.The total QOL score of postoperative radiotherapy patients was 859.8,while that of postoperative radiotherapy patients was 902.3,with statistical difference（P<0.05）.The total QOL score of those receiving postoperative chemotherapy was 870.5,and that of those without postoperative chemotherapy was 851.2,showing no statistical difference（P>0.05）.The QOL total score of the surviving spouse was835.2,and the QOL total score of the bereavowed spouse was 751,with no significant difference（P>0.05）.The total QOL score of those without flap repair was 871.6,that of those with free flap repair was 820.1,and that of those with pedicle flap repair was 820.9,showing no statistical difference（P>0.05）.The total score of QOL of non-invasive buccal muscles was 853.3,and that of invasive buccal muscles was 810.7,with statistical difference（P<0.05）.Conclusions1.Gender,age,education level,marital status,chemotherapy after operation and the location of tumors around the cheek are not important factors in long-term quality of life.2.Smoking,clinical staging of tumors,post-operative radiotherapy,choice of neck lymph node dissection and invasion of buccal muscles by tumors all affect the overall quality of life of patients with buccal cancer 5 years after operation,which is an important factor affecting the long-term quality of life of patients after operation.