Analysis Of Influential Factors Of Intracranial Infection After Craniotomy For Cerebellopontine Angle Lesions

Purpose:Intracranial infection after neurosurgery craniotomy is in co mmon,and the infection rate of posterior fossa craniotomy surgery is highe r.The infection after craniotomy in cerebellopontine angle area(CPA)lesi ons is also obvious,but the literature about that is less.This study is to an alysis the cause of intracranial infection after craniotomy in CPA lesions i n order to reduce the infection rate of this area.Method:398 patients with CPA lesions who have underwent cranioto my surgery in The First Affiliated Hospital Of Guangxi Medical Universit y between January 1,2015 and December 31,2018 were selected as the da ta.All of them were the first time of underwent operation.Analyze 17 poss ible related factors to get the result.Results:The univariate analysis showed that the length of hospital st ay,the opening of mastoid air chamber during surgery,the duration of surgery,postoperative cerebrospinal fluid leakage,external ventricular dra inage tube,and external ventricular drainage tube were P<0.05,which w ere statistically significant.The univariate and multivariate Logistic regressi on analysis showed that the duration of operative>4h,intraoperative mastiod air chamber opening,postoperative cerebrospinal fluid leakage,extern al ventricular drainage tube,and the duration of preoperative hospitalizatio n ≥7d were P<0.05,which were independent risk factors for intracranial infection after craniotomy about CPA lesions.From high to low,the rank of risk were postoperative cerebrospinal fluid leakage(OR=12.568),mast oid air chamber opening(OR=5.017),external ventricular drainage tube(OR=4.459),hospitalization duration ≥7d before surgery(OR=0.416),and surgery duration>4h(OR=0.401).Conclusion:The independent risk factors of the CPA area disease co mplicated with intracranial infection after operation including the postopera tive cerebrospinal fluid leakage,postoperative intraventricular external drai nage tube,the length of surgical operation time,the open of mastiod dur ing the operation,hospitalization time before surgery.In the treatment of i ntracranial infection after craniotomy,the treatment time increases with th e extension of the duration of the external ventricular drainage tube.Prolon ged indwelling of subcutaneous drainage tubes will increase the risk of in tracranial infection.