Application Of Enhanced Recovery After Surgery In The Perioperative Period Of Gastric Stromal Tumors

Background and purposeGastrointestinal stromal tumors are the most common non-epithelial source of gastrointestinal mesenchymal tumors.At present,the treatment of Gastrointestinal stromal tumors is mainly based on surgical resection and assisted in the comprehensive treatment mode of perioperative medication.The concept of enhanced recovery after surgery(ERAS)is a method of integrating and improving preoperative,intraoperative,and postoperative treatments by applying a series of measures during the perioperative period to maximize the blocking or reduction of perioperative trauma to the body and the stress response to make patients recover faster.Therefore,exploring the application of the ERAS concept in the perioperative management of gastrointestinal stromal tumor surgery,to evaluate its clinical effects and explore whether there is an advantage and to find the clinical value of applying the ERAS concept in perioperative period of gastrointestinal stromal tumor.Materials and MethodsThis study retrospectively analyzed 61 patients with gastrointestinal stromal tumor resection from January 2016 to December 2018.Thirty-four patients underwent laparoscopic gastrointestinal stromal tumor resection with traditional perioperative methods(for short as the traditional group),and 27 patients underwent laparoscopic gastrointestinal stromal tumor resection with ERAS perioperative methods(for short as the ERAS group).The clinical indicators of the two groups of patients required for the study,including age,gender,weight and location,staging and surgical methods;as well as the operation time,intraoperative blood loss,intraoperative fluid volume;the time off-bed activity,first aerofluxus time,hospitalization time,complications;record the patient’s white blood cells(WBC),procalcitonin(PCT),c-reactive protein(CRP)before surgery,1st day and 4th after surgery,and perform statistical processing and evaluation analysis.Statistical methodThe research data was analyzed and processed using SPSS 25 software.The measurement index data were expressed as mean±standard deviation(?x±s),the measurement data was in accordance with the normal distribution,and the difference between the two groups was compared using the independent sample t test;the comparison between the counting data groups was performed by chi-square test,the difference between groups Theχ~2 test or Fisher’s exact probability method was used.P<0.05 indicates that the difference was statistically significant.Result1.After statistical analysis,the gender ratio,age,clinical symptoms,tumor location,pathological grade,and surgical procedure were compared between the ERAS group and the traditional group.The differences were not statistically significant(p>0.05),indicating that the two groups Comparable.2.The amount of rehydration in the ERAS group and the traditional group shows that ERAS group was significantly lower than that in the traditional group.The ERAS group was significantly earlier than the traditional group in the exhaust time,the time of the ground,the hospital stay,the oral eating time,and the defecation time.The difference was statistically significant(p<0.05).3.There were no statistically significant differences in preoperative CRP,PCT,and WBC levels between the ERAS group and the conventional group.The levels of CRP,PCT,and WBC in the ERAS group were lower than those in the traditional group(p<0.05).ConclusionCompared with traditional perioperative management,ERAS concept can improve the postoperative rehabilitation of patients with perioperative management,increase the incidence of postoperative complications,and significantly reduce the postoperative stress response,which is more advantageous.