Study On TCM Syndrome Law Of Chronic Atrophic Gastritis With Anxiety And Depression

Objective:The research aimed to summarize the distribution of TCM syndromes in patients with chronic atrophic gastritis(CAG)accompanied by anxiety and depression,and to explore the characteristics of its syndromes and pathogenesis,so as to provide references for the treatment of such diseases with TCM.Methods:This topic research object for during March 2018 to January 2019 Jiangsushen province,Chinese medicine hospital outpatient and the inpatient treatment of digestive diseases in patients with chronic atrophic gastritis with anxiety and depression,combined with literature study and expert discussion,to develop TCM syndrome observation scale,record the clinical data of patients eligible for inclusion and the four diagnostic information,database,input data using the statistical software SPSS analysis of the frequency and the frequency of each variable,using the factor analysis method to extract the main factor,the clustering analysis method to extract the symptoms,and according to the proposed standard of syndrome differentiation of the clustering results are,The distribution characteristics of chronic atrophic gastritis with anxiety and depression were obtained.Results:1.General data analysis:1.(2)age:the age distribution is wide,the smallest is 20 years old,the largest is 85 years old,the age distribution is mainly 51-60 years old,the median age is 53 years old;(3)gastroscopy pathology:the results showed that mild CAG(68.0%)and mild intestinal metaplasia(71.8%),dysplasia accounted for only 6.2%of the total cases;(4)state distribution of anxiety and depression:in 241 patients,the main state with anxiety(54.8%)is the main,the combined state(17.8%)is the least;There was no significant difference in gender distribution(P<0.05).The age distribution was basically the same,the average age of anxiety state was low(51.2years old),and the age of anxiety and depression combined state was high(56.4years old).Pathologically,dysplasia was mainly distributed in patients with anxiety.The results were statistically significant(P<0.05).2.The analysis of the four diagnostic information:this study suggests that the disease common symptoms are swollen belching frequency(74.3%),the diagnosis is full or pain(71.8%),insomnia,much dream god(58.9%),fatigue(53.5%),defecate pond stay thin(52.7%),eating less(48.1%),dry mouth(49.0%),and the diagnosis to home(47.7%),symptoms due to emotional factors induce or aggravate(44.8%),postprandial increase(42.3%),ribs bloated with discomfort or dull pain(41.9%).The tongue with high frequency was pink(63.1%),red(21.2%),white(56.0%)and greasy(24.9%),and the tongue with tooth marks accounted for 66.4%of the total cases.The first two pulse types were veinule(55.6%)and chord(49.8%).3.Multivariate statistical analysis:(1)factor analysis:the disease location was mainly in the stomach,spleen,liver,followed by the heart and lung;The deficiency syndrome is mainly composed of qi deficiency,blood deficiency,Yin deficiency and Yang deficiency.The evidence is mainly composed of qi stagnation,solid heat,damp heat,blood stasis and phlegm.Liver depression and spleen deficiency are the basic pathogenesis of the disease.Compared with chronic atrophic gastritis,deficiency of heart and spleen and spittoin stagnation of qi are the specific pathogenesis of this disease.(2)cluster analysis:through cluster analysis,nine syndromes of liver and stomach qi stagnation,spleen and stomach qi deficiency,stomach^Yin deficiency,spleen and stomach deficiency and cold,liver and stomach heat retention,spleen and stomach damp-heat,stomach collaterals and blood stasis,qi stagnation and phlegm,heart and spleen deficiency were summarized.4.Distribution of syndrome types:(1)syndrome type distribution:there are 9 main TCM syndrome types,among which liver and stomach qi stagnation syndrome(44.8%)and spleen and stomach qi deficiency syndrome(39.4%)are the main ones;(2)syndrome type combination:the single syndrome type(45.6%)and the two syndrome combination(46.5%)were the main types,in which the spleen and stomach qi deficiency syndrome combined with liver and stomach qi stagnation syndrome(32.1%)were the main types.(3)correlation between gender,age and syndrome type:gender has differences in the distribution of liver and stomach heat retention syndrome(P<0.05),mainly female,age have differences in the distribution of stomach collature-stasis syndrome(P<0.05),the average age is 57 years old;(4)the correlation between anxiety and depression and syndrome type:deficiency of stomach Yin,liver and stomach heat retention syndrome are mainly distributed in the anxious state;Spleen and stomach deficiency and cold syndrome,qi depression and spittoon syndrome were mainly distributed in depression.Blood stasis syndrome was mainly distributed in the state of anxiety and depression combined with the state,and there was a difference(P<0.05).Conclusion:This disease mainly includes liver and stomach qi stagnation syndrome,spleen and stomach qi deficiency syndrome,stomach Yin deficiency syndrome,spleen and stomach deficiency and cold syndrome,liver and stomach heat retention syndrome,spleen and stomach damp-heat syndrome,stomach collaterals and blood stasis syndrome,qi stagnation and phlegm syndrome,nine syndrome types of heart and spleen deficiency syndrome.The location of the disease was mainly in the stomach,spleen and liver,followed by the heart and lung.The deficiency syndrome is mainly composed of qi deficiency,blood deficiency,Yin deficiency and Yang deficiency.The evidence is mainly composed of qi stagnation,solid heat,damp heat,blood stasis and phlegm.Liver depression and spleen deficiency are the basic pathogenesis of the disease.Compared with chronic atrophic gastritis,deficiency of heart and spleen and spittoin stagnation of qi are the special pathogenesis of this disease.In patients with anxiety state,heat syndrome was the main disease,including deficiency heat and solid heat,and the distribution of deficiency syndrome of gastric Yin deficiency and stasis heat of liver and stomach was the main disease.Patients with depression were mainly characterized by deficiency and cold syndrome and qi stagnation syndrome,and mainly distributed by spleen and stomach deficiency and cold syndrome and qi stagnation and phlegm coagulation syndrome.