The Application Of IVIM-DWI In The Cerebral Alveolar Echinococcosis And Its Infiltration Zone

Objective:To explore the value of intravoxel incoherent motion diffusion-weighted imaging（IVIM-DWI）in quantitative evaluation of the marginal zone of alveolar echinococcosis（CAE）.Methods:Collect CAE patients who meet the inclusion criteria.Routine MR and IVIM-DWI scans were performed.Thirteen b values（0,20,50,100,200,400,800,1800,2500,3000,3500,4000s/mm²）were used for IVIM-DWI.Substantial areas,marginal areas,edema areas（5mm,10mm,15mm）and contralateral normal areas（pairs）were measured.The standardized apparent diffusion coefficient(ADC _standard),pure diffusion coefficient ADC _slow（D）,false diffusion coefficient ADC _fast（D*）and perfusion fraction（f）of brain parenchyma were analyzed statistically.Results:There was no significant difference in ADC _standardtandard value,ADC _fastast value,ADC _slowlow value and f value between the parenchymal area and the marginal zone of the lesion;there was significant difference in ADC _standardtandard value between the parenchymal area and the 10 mm edema area and the control area（P<0.05）;there was significant difference in ADC fast value between the 5 mm edema area and the control area（P<0.05）;there was significant difference in ADC _fastast value between the parenchymal area and the control area（P<0.05）.There were significant differences in ADC _slowlow values between marginal zone and control area,edema area（5mm,10mm,15mm）and control area（P<0.05）;F values between parenchymal zone and edema area（5mm,10mm,15mm）,control area and edema area（5mm,10mm,15mm）were statistically significant（P<0.05）;there were no significant differences in the results of other groups（P>0.05）.Conclusion:Some parameters of IVIM-DWI(ADC _fastast and ADC _slow)are helpful to define the extent of CAE infiltration zone and provide objective imaging basis for the formulation of CAE surgical plan and prognosis analysis.