Multi-Parameter Quantitative Analysis Of Lung Cancer And Squamous Cell Carcinoma By Energy Spectrum Imaging

Objective: To explore the application of multi-parameter parameters of energy dispersive CT in differentiating squamous cell lung cancer from adenocarcinoma.Methods: 54 patients with pulmonary space occupying lesions were scanned by energy spectrum CT.All patients were confirmed by operation and pathology.35 cases of adenocarcinoma and 19 cases of squamous cell carcinoma.The CT value,iodine content and effective atomic number of 40 KV,100 KV and 70 KV in arterial lesions and regions of interest of aorta were measured by GSI viewer software.The slope of energy spectrum curve,iodine value and effective atomic number of 70 KV in arterial lesions were calculated.Standardized CT values and standardized iodine values(NIC)at 70 KV were analyzed by two independent samples t test,and the reference indexes were evaluated by pathological gold standard.Results: The average age of lung cancer patients was 61.64 years,and that of squamous cell cancer patients was 62.9 years.The average age of patients with adenocarcinoma was 61 years old,including 30 males and 24 females,including 19 squamous cell carcinomas,35 adenocarcinomas,11 males and 8 females;12 males and 23 females were adenocarcinomas,and there was no statistical difference in gender balance between the two groups: the x 2 value was 2.807,the P value was 0.094,the P value was > 0.05.Comparisons of lower standardized iodine content(NIC),slope of energy spectrum curve,iodine value of lesions and standardized CT value: 1)NIC of arterial adenocarcinoma was larger than that of squamous cell carcinoma,with statistical significance P < 0.05;2)K of energy spectrum curve of arterial adenocarcinoma was larger than that of squamous cell carcinoma,with statistical significance P < 0.05;3)iodine content of lesions of arterial adenocarcinoma was higher than that of squamous cell carcinoma.The difference was statistically significant(P < 0.05).4)The number of effective atoms in arterial adenocarcinoma was larger than that in squamous cell carcinoma,and the difference was statistically significant(P < 0.05).5)The standardized CT value of arterial adenocarcinoma was larger than that of squamous cell carcinoma,and the difference was statistically significant(P >(0.05).Conclusion: There are differences between squamous cell carcinoma and adenocarcinoma of lung in multi-parameters of energy spectrum imaging,which is valuable in differentiating squamous cell carcinoma from adenocarcinoma of lung.