Comparative Analysis Of The Clinical Characteristics Of Primary Biliary Cholangitis And Non-alcoholic Fatty Liver Disease

Objective:To study the relationship between the clinical manifestation,BMI,age,blood routine,liver function and serum antibody between patients with primary biliary cholangitis and nonalcoholic fatty liver disease.Methods:A total of 91 patients with primary biliary cholangitis and147 patients with non-alcoholic fatty liver disease were enrolled in our hospital for 2012.1months of-2016.12 months,and147 patients with nonalcoholic fatty liver disease were analyzed.The difference between the two patients and the data of the clinical,general and laboratory tests were analyzed and compared relationship.Results:There were 238 cases in the group,of which 91 were in group PBC(15(16.5%)of males,76(83.5%)in females,average age(48.30 + 8.84)),147 in NAFLD(90(61.2%),57(38.2%),and average age(44.05 +12.26)).The most obvious clinical of 91 patients with PBC were asthenia 20.9%(19/91),jaundice15.4%(14/91)and pruritus 13.2%(12/91).The most obvious clinical symptoms of NAFLD were liver discomfort 19.7%(29/147),asthenia 18.4%(27/147)and abdominal distention7.5%(11/147).PBC patients and fatty liver patients BMI,age,abdominal circumference,RBC,HB,CHOL,HDL,TG,AST,γ-GGT,ALP(P<0.05),there is a significant difference between the two groups of data.There was no significant difference in residual index data.PBC patients were mainly ANA antibody and AMA antibody,and 1:1000 titers were the main ones(38/74).The fluorescence model is dominated by the granular granular type(39/74).Conclusion:1.There were gender differences in PBC patients and NAFLD patients;there was no significant difference in clinical symptoms between the two groups;2.compared with NAFLD patients,the abnormal degree and dispersion of liver function enzyme spectrum in PBC group is higher;3.The positive rate ofAMA-M2 in group is lower than that at home and present;4.ANA antibody positive in low titer should be identified with NAFLD;...