The Long-term Prognostic Influence Of Drug Therapy And Interventional Therapy To Acute Non-ST Segment Elevation Acute Myocardial Infarction

Objective : To discuss the long-term prognostic influence to acute non-ST segment elevation acute myocardial infarction with different treatment regimens.Methods:use the retrospective cohort study method,it was 716 cases of patients with acute non-st-segment elevation myocardial infarction that listed in the Heart Center of the first affiliated hospital of Xinjiang Medical University,which were divided into two groups: interventional therapy group(317 cases)and drug treatment group(399 cases).Multivariate COX regression analysis was used to adjust the influence of confounding factors.Results:in the study,a total of 45patients(6.25%)died,including 25 patients(3.4%)with central source death(including malignant arrhythmia,acute left heart failure,and fatal myocardial infarction).There were 51 cases of hemorrhage(7.1%)and 205 cases of MACCE(28.6%).The differences in MACCE,stroke and readmission between the interventional therapy group and the drug therapy group were statistically significant(P < 0.05).By COX regression model analysis for MACCE as dependent variable,with smoking,drinking,creatinine,low density lipoprotein cholesterol(ldl-c),lipoprotein a and troponin T(CTnT)and left ventricular diameter,hypertension,diabetes,at the end of the PCI treatment as independent variables,statistical result analysis shows that the PCI therapy(OR = 0.848,95% CI: 0.386 0.876,P = 0.009),lipoprotein a(OR= 1.001,95% CI: 1.000 1.002,P = 0.038),smoking(OR = 1.430,95% CI:1.012-2.007,P=0.039)and diabetes mellitus(OR=5.587,95%CI: 3.501-8.917,P=0.000)were associated with the risk of long-term MACCE events in patients with NSTEMI.Conclusion:compared with drug therapy,PCI can improve the long-term prognosis of patients.