| Objective This study was designede to translated the English version of Chemotherapyinduced Alopecia Distress Scale for breast cancer into Chinese,and provide basis for improving the assessment of chemotherapy-induced alopecia distress and management of symptoms in patients with breast cancer.The scale was applied to the clinic.To investigate chemotherapy-induced alopecia distress、medical coping modes and quality of life among patients of breast cancer,to explore the relationship among thress aspects,and provide reference for clinical interventions.To explore the effects of cosmetic therapy on chemotherapy induced alopecia in patients with breast cancer,lays the foundation for future clinical practice and provides practical guidance for improving the quality of life of breast cancer patients.Methods 1.After obtaining the original author’s authorization,the original scale was translated and back translated.The reliability and calidity of CADS were tested in 160 women with breast cancer undergoing chemotherapy.2.Totally 183 breast cancer patients were investigated from a hospital from Tianjin in June 2017 to September 2017 by convenience sampling method.The breast cancer patients were investigated with General information questionnaire、Chemotherapy induced Alopecia Distress Scale 、 Medical Coping Modes Questionnaire and Functional Assessment of Cancer Therapy – Breast cancer.To explore the relationship among chemotherapy-induced alopecia distress、medical coping modes and quality of life.3.This study used convenience sampling and enrolled 80 patients with breast cancer undergoing chemotherapy.The patients in the control group received routine care,while the patients in the experimental group received cosmetic therapy.The cosmetic therapy includes 4 contents: health education 、make up Lesson、peer exchange and take a photo.The chemotherapy induced alopecia distress,Medical copying models and quality of life were compared between two groups.Results 1.The Chinese version of CADS included 17 items and 24 factors were extracted by factor analysis,which could explain 56.108% of the total variance.The range of correlation coefficient between each item and its own dimension is 0.407~0.870.CFA showed the fit indexes of a second-order model,including TLI=0.944,CFI=0.956,RMR=0.058.Cronbach’sα coefficient was 0.864,while Guttman split-half and test-retest reliability were 0.775 and 0.931 in our study.2.One hundred eighty-three breast cancer patients participated in the study.The total score of CADS was(24.45±7.24)scores.There were significant difference between CADS scores with difference chemotherapy,chemotherapy time,degree of haie loss and the time of illness.3.One hundred eighty-three breast cancer patients were investigated by Functional Assessment of Cancer Therapy – Breast cancer.The total score of FACT-B was(81.36±14.78)scores.There were significant difference between CADS scores with difference Income per month,Job,degree of hair loss,surgery,age and the time of illness.4.Pearson correlation analysis indicated that the CADS was significantly associated with confrontation,avoidance,Acceptance-resignation and quality of life(P<0.05).Hierarchical regression analysis indicated that confrontation and avoiding play an intermediary role in CADS and quality of life.6.After 1 week of cosmetic therapy,the scores of Confrontation and quality of life in the experimental group were significantly higher than those in the control group(P<0.05);the scores of chemotherapy induced alopecia distress and avoidance coping in the experimental group were significantly higher than those in the control group(P<0.05).However,there was no statistically significant difference in physical aspect and Acceptance-resignation between the two dimensions(P>0.05).Conclusions 1.The Chinese version of CADS is reliable and valid,and can be used to measure distress of chemotherapy-induced alopecia.2.Health care workers should pay more attention to breast cancer patients who have religious beliefs,high education level,TEC program,1 to 2 cycles of chemotherapy,and III degree hair loss.Health care workers popularize knowledge of hair loss prevention and counseling,help effectively cope with mutations and improve patients’ physical and mental problems.2.CADS in breast cancer patients can directly or indirectly predict quality of life through coping modes.Coping modes is a direct predictor of quality of life.Facing and avoidance coping styles can alleviate the negative effects of CADS on quality of life.3.Cosmetic therapy can effectively improve the patient’s degree of chemotherapy induced alopecia distress,guide their positive coping modes,ease the avoidance coping style,and ultimately improve the quality of life. |