The General Situation Of Liquid Biopsy In The Study Of Glioma

Objective:Introduction of the liquid biopsy technique and the general situation in the study of glioma so as to further guide its diagnosis,treatment and prognosis.Content:Liquid biopsy is a new method of cancer detection in recent years.It is fast,simple,minimal invasive,of good repeatability and vigorous development.Glioma is the most common primary intracranial malignant brain tumor with a high degree of malignancy.Even with the standardized treatment prescribed in the current guide,patients are still faced with a recurrence of the tumor so far as to death.We consult journal reference and treatment guide in domestic and foreign of last several years,then summarize some kinds of techniques for liquid biopsy and its application in the diagnosis,treatment,prognosis,recurrence monitoring and new directions of glioma,including the origin,biological characteristics and the application of circulating tumor cells,circulating tumor DNA and exosomes in glioma research.Methods and results: Take advantage of the network resources to look up the journal magazines and treatment guidelines at home and abroad through Wanfang Data knowledge service platform,CNKI,Pubmed and other websites in recent years,then carefully read and translate.Conclusion: Liquid biopsy has great potential for clinical application in glioma,which will not be ignored,and it will become an important part of precision medicine in the field of cancer.We should continue to search for better enrichment and detection technology.