Influence Of Goal-directed Fluid Therapy On Prognosis After Plasmakinetic Energy Transurethral Resection Of Prostate Surgery In Elderly Patients With Hypertension

PURPOSE:We aimed to investigate the influence of perioperative goal-directed fluid therapy（GDFT）on the prognosis of elderly patients with benign prostatic hyperplasia and hypertension.METHODS:Sixty elderly patients（60⁸0 years old）with primary hypertension who received plasmakinetic energy transurethral resection of prostatesurgery.Selected patients were divided randomly into two groups,comprising a conventional intraoperative fluid management group（group C,n=30）and a GDFT group（group G,n=30）.Patients in group C according to the sixth edition of Anesthesiology Miller underwent routine fluid therapy.Patients in group G were infused with 200 ml hydroxyethyl starch in 15 minutes under the FloTrac/Vigileo monitoring system,with stroke volume variation between 8%and 13%and DO₂I≥500ml/min.m²,while those in group C were infused with crystalloids or colloids according to MAP、HR、CVP.Hemodynamics、tissue perfusion laboratory indicators、utilization of vasoactive agents in both groups were recorded after the operation.RESULTS:Compared with group C,the average intraoperative intravenous infusion quantity in group G was significantly reduced（1830±348ml versus2075±466ml,P<0.05）,whereas average colloid fluid volume was significantly increased（1020±210ml versus 569±138ml,P<0.05）.In addition,there were more patients exhibiting intraoperatively and postoperatively stable hemodynamics and less patients with low blood pressure in group G.Postoperative complications were less frequent,and the time of postoperative hospital stay was shorter in group G.No significant differences were observed in mortality between the two groups.CONCLUSION:Our research showed that GDFT stabilized perioperative hemodynamics and reduced the occurrence of postoperative complications in elderly patients who underwent plasmakinetic energy transurethral resection of prostate surgery.