Study On The Correlation Between Irregular Menstruation And TCM Syndrome Type Of WD Patients During The Period Of Birth

Objective: To investigate the distribution of five basic syndromes of WD in women with irregular menstruation during the growth period,and six items of serum sex hormones in the third days of menstruation,and to explore the correlation between six test items and common syndromes in traditional Chinese medicine(WD).Methods:the patients with hepatolenticular degeneration hospitalized in the First Affiliated Hospital of Anhui University of traditional Chinese medicine from February 2016 to October 2017 were selected.On the basis of WD TCM syndrome diagnostic criteria(according to Yang Wenming Wilson’s treatment program)to determine the syndrome type of damp-heat,phlegm and blood stasis,liver qi stagnation,liver and kidney yin deficiency,spleen kidney yang deficiency syndrome criteria of TCM syndrome type,parallel menstrual period third days serum sex hormone six detection and statistical analysis.Results:1.180 cases of WD TCM syndrome differentiation of irregular menstruation proportion order: 27.78(50 cases),25.56% liver qi stagnation syndrome(46 cases),17.22%damp heat syndrome(31 cases),phlegm and blood stasis 16.11%(29 cases),spleen kidney yang deficiency syndrome 13.33%(24 cases),the liver and kidney yin deficiency gas,liver stagnation syndrome is the most common.2.WD irregular menstruation distribution in all ages,to menstruation and menstruation,menorrhagia and menstrual period is most common,accounting for81.11%,while relatively rare manifestations of uterine bleeding.3.The age of onset of irregular menstruation of women in 3.WD period was mainly between 26~35 years,accounting for 57.22%.The average age distribution of WD patients with different TCM syndrome types was not statistically significant(P >0.05).4.WD commonly used in the three types of brain type,liver type and liver-brain type,most of the patients with liver-brain type irregular menstruation.5.The growth period of 5.WD female menstruation and menstruation in liver kidney yin deficiency,liver qi stagnation syndrome more common,more common menorrhagia,menstruation in phlegm and blood stasis syndrome,spleen kidney yang deficiency and damp heat syndrome.6.WD of patients with irregular menstruation,six days of menstrual period,third days of serum sex hormones,the average level of estradiol in patients with liver kidney yin deficiency is low.The average serum FSH level in patients with liver kidney yin deficiency is third days higher than that in other groups(P < 0.05).The level of serum luteinizing hormone(P < 0.05)was higher in the third day period of the spleen and kidney yang deficiency syndrome.The number of progestin,prolactin and testosterone was not statistically significant(P > 0.05).Conclusion:1.The syndrome of liver and kidney yin deficiency and liver qi stagnation was the most common in the syndrome differentiation of the 1.period of menstruation in the 1.childbearing period,and the syndrome of liver qi stagnation and liver qi stagnation syndrome were more common.The excess menstruation and menorrhagia were found in the syndrome of phlegm and stasis,spleen kidney yang deficiency syndrome and damp heat syndrome.2.The distribution of serum FSH,LH and E2 in the TCM syndrome type of WD is different.The average level of FSH in the patients with liver kidney yin deficiency is high,the average level of E2 is low;the average level of LH in the patients with spleen and kidney yang deficiency is high,which may result in the abnormal deposition of copper and lead to the hormone secretion and metabolic disorder in the body.