Association Between Obesity Phenotypes And Incident Hypertension Among Chinese Adults

Objectives:To explore the association between obesity phenotypes and the risk of hypertension among Chinese adults.Method:Datas were collected from China Health Nutrition Survey(CHNS).Participants aged 18 to 65 at baseline who took parted in both suveys in 2009 and 2011 were included in the study.According to IDF and HOMA-IR criteria in combination with BMI and WC,we divided study participants into four groups:Metabolically healthy nonoverweight/obesity(MHNO),metabolically healthy overweight/obesity(MHO),metabolically abnormal nonoverweight/obesity(MANO),and metabolically abnormal overweight/obesity(MAO).Logistic regression model was conducted to estimate the risk of hypertension with obesity phenotype.Result:Of 4604 participants at baseline,467 participants developed hypertensio n during the 2-year follow up period.Based on IDF-BMI criterion,MHO,MA NO,and MAO groups show significantly increased risk for hypertension,the O Rs(95%CI)were 1.78(1.39-2.27),1.71(1.02-2.86),and 3.35(2.54-4.42),respectively,when comparing with MHNO group.Based on IDF-WC criterion,Metabolicall y unhealthy non-obesity group and Metabolically unhealthy obesity group show ed significantly increased risk for hypertension,the ORs(95%CI)were MHNO:1.73(1.31-2.27),2.05(1.46-2.88),3.38(2.58-4.43),respevtively.Based on IR-BMI criterion,MHO,MANO and MAO showed significantly increased risk for hype rtension,the ORs(95%CI)were 2.35(1.80-3.06),2.71(1.22-2.29),3.83(1.99-3.48),respectively.Based on IR-WC criterion,Metabolically healthy obesity group,Metabolically unhealthy non-obesity group and Metabolically unhealthy obesity group showed significantly increased risk for hypertension,the ORs(95%CI)were 2.38(1.82-3.14),1.73(1.26-2.37),2.62(1.97-3.49),respectively.Conclusion:Obesity phenotypes were significantly associated with the development of hypertension among Chinese adults.