The Extract Technology Reform And Quality Analysis Of Breviscapine

Erigeron breviscapus Compositae Erigeron breviscapus dry grass(Erigeron breviscapus(Vant.)Hand-Mazz).Withunblocking collateral,promoting the circulation and relieving pain,expelling wind and cold effect.Effective material parts of Erigeron breviscapus extract of Erigeron breviscapus,Received in the 《Pharmacopoeia of the People’Republic of China》 2015 first edition,the main component of scutellarin.The extract preparation of various drug for cardiovascular disease,an important raw material for many varieties of Chinese medicine and compatibility,have good sales share in the domestic pharmaceutical market.Hubei turnock Pharmaceutical Co.,Ltd.and the laboratory implementing combination of production,teaching and research of Erigeron breviscapus extract preparation technology research on the reform,in order to reduce the original preparation process of environmental pollution problems;in addition,the paper through the quality analysis for the process of reform of the preparation of breviscapine extract is carried out on,to further improve the quality control standard.In various factors affecting the efficiency of Erigeron breviscapus extract,the different extraction methods,different extraction solvents,different extraction temperature,different extraction time were comparative study;the orthogonal test and single factor research methods were employedin the study,on the impact of macroporous adsorption resin separation purification of the extract of breviscapine related factors were studied and optimized;in order to improve the extract of Erigeron breviscapus Aesculetin content,by solvent extraction of scutellarin extract of purification of.The research were obtained reliable technical parameters,and was verified by experiment,for after the transition to industrialization production provides parameter basis.Reference the《Pharmacopoeia of the People’Republic of China》 2015 first edition,a collection contains the quality standard of traditional Chinese medicine extract technology requirements,the traits of scutellarin extract,identification,examination(including moisture,total ash and insoluble ash,extract,loss on drying,residue on ignition,macroporous resin organic residues residue,heavy metals and harmful elements such as),content determination item were studied,formulated the more perfect quality control standard.The research method is simple and easy to operate,to reproduce the good,strong reliability,can effectively control the breviscapine extract quality.