Analysis And Prediction Of Research Status Of Aristolochic Acid At Home And Abroad Based On Informationmetrics

Objective: From the perspective of information analysis,using qualitative and quantitative statistical methods,using information analysis software,a large number of literature data on studies of aristolochic acid at home and abroad were collected and compared with professional visual analysis to understand its development context and to ascertain its research.Hotspots and frontiers and predicting future research directions;exploring domestic cooperation in aristolochic acid research and powerful leaders and leading agencies to help researchers find partners that are close to or complementary to their own research;Potential relationships between disease and drugs,prediction of undetected toxic drugs or plants,and susceptible populations.Method: In this topic,all the Chinese documents related to Aristolochic Acid were retrieved from CBM,CNKI,Wanfang and Weipu,and all related foreign languages were retrieved from Pub Med,Science Driect,Springer,and web of science.literature.Combining bicomb,excel,citespace,ucinet and other software research literature,qualitative analysis,quantitative analysis,statistical forecasting methods,comparative analysis and induction of the earliest published articles,reports,and latest journals and high-yield authors,and interpretation of the main authors.Popular research areas;scientific and quantitative measurement of the annual volume of puberty aristolochic acid at home and abroad,research progress,distribution of research institutions,and major research directions;analysis of the overall evolutionary trends in the field,major publishers and institutions,etc.;The relevant case information in the statistics and analysis,statistical AAN concentrated age of onset,high diagnosis and treatment rate agencies,AAN high incidence areas,the main pathogenic drugs,etc.to deepen the understanding of AA aspects of relevant researchers to help their subsequent research and development and The formulation of relevant decisions.Result: 1.China’s research on AA first started in 1957,and it has now entered a period of stable development after experiencing the bud period from 1957 to 1997 and the rapid development period from 1998 to 2007.Zhang Jinyuan,Shen Yipu and Feng Jiangmin are the leading figures in the AA research field.In the cooperation of the author,there are five authors cooperation networks,including Shen Yipu,Zou Wanzhong,Chen Wen,Wang Lining,Feng Jiangmin,Li Wei,Chen Xiuzhen,Qiu Yunping,Li Li,Rao Xiangrong,Lou Fengchang,and Peng Guoping are represented in the cooperation network.Internal independent cooperation research has low level of cooperation with other groups or individuals.It belongs to the same geographical area but the cooperation between different organizations is small.There is almost no relevant cooperation.From a macro perspective,researchers can see that the researchers have developed steadily and uniquely in their research fields.There is not much big breakthrough and innovation,and the relevant theory or technology is not yet mature as a whole,and it is impossible to realize the cooperation in research direction or technology.About aristolochic acid nephropathy(aan)is a significant hot spot for AA research.Its hot research topics include etiological study and treatment of AA,AA-related component analysis,and source of AA.It is predicted that in the future domestic research on AA will focus on liver injury or other organ damage.At present,the institution that receives the most AAN patients is the First Affiliated Huaian First Hospital of Nanjing Medical University.Coastal areas such as the East Three Provinces are areas with high incidence of AAN.Guanxin Suhewan and Longdanxiegan Pills are the main pathogenic factors of AAN.Most patients with AAN are middle-aged and the average age is 47.98 years.The prevalence of women is higher than that of men.2.The international research on AA first started in 1953,and the overall trend tended to rise steadily,with a steady development stage,and 6 years as a small maturation cycle.Schmeiser Heinz H and Arlt Volker M are international leaders in AA research.State University of New York in the US is a high-yielding and leading organization in the AA-related field.It is the world’s largest system of higher education and the largest and most comprehensive state university education system in the United States.In addition,China,the United States,and the United Kingdom rank among the top three in the world for AA.Globally there are 73 research directions for AA,and the top three are pharmacology,biochemistry,molecular biology and toxicology.Conclusion: 1.The domestic AA related research fever has slowed down in recent years,and international research has remained stable.2.The domestic AA-related fields are mainly institutional-based small-group cooperation,with low-level cooperation.3.The hot area of global AA research is the pharmacology and toxicology of AA.4.China,the United States,Germany,and other countries have obvious advantages in AA research and have strong effective competitiveness.