| Objective:To explore the clinical value of perirenal ice water technique in the protection of ipsilateral renal function during the retroperitoneal laparoscopic partial nephrectomy（RLPN）.Methods:From March 2014 to January 2017,41 patients with renal tumor undergoing retroperitoneal laparoscopic partial nephrectomy were chosen in our hospital and divided into study group（n=20）and control group（n=21）.The patients in study group were treated with the RLPN under the protection of perirenal ice water,while cryogenic technique was not used in control group.The operation time,renal ischemia time,blood loss,preoperative and postoperative serum creatinine,and blood urean itrogen were compared.The glomerular filtration rate（GFR）of bilateral kidneys and affected kidneys were measured with 99mTc-DTPA.Results:All the operations were successfully performed.There were no blood transfusions and no serious complications,such as postoperative bleeding,acute renal failure,Urine leakage.There was no significant differences in the operation time,renal ischemia time,blood loss between the two groups（P>0.05）.There was no statistical difference in blood urean itrogen and serum creatinine between the two groups before and after operation（P>0.05）.There was no statistical difference in the total renal GFR between the two groups before and after operation（P>0.05）.There was no significant difference in the affected kidney GFR between the two groups before operation.At 3 month after the surgery,the affected kidney GFR in study group was significantly higher than that in control group.All the patients were followed-up for 3 to 24 months,no recurrence,distant metastasis,complications caused by cryogenic technique were observed.Conclusion:Renal hypothermia technique via perirenal ice water in retroperitoneal laparoscopic partial nephrectomy can reduce renal ischemia reperfusion injury and effectively protect the ipsilateral renal function.It is reliable and worthy of romotion. |
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