The Effects Of CSⅡ In Perioperative Burn Patients With Diabetes

Objective: to investigate the effects of CSⅡ in perioperative burn patients with diabetes.Methods: Total 80 third-degree burn patients with type 2 diabetes who were hospitalized in our hospital during 2010-2015 were enrolled.Patients were treated with eschar escharectomy and autologous edge-thickness skin grafting 3-5 days after the injury.Patients were divided into CSⅡ and MDSI groups by random numbers.Patients in CSⅡ group were treated with continuous subcutaneous insulin infusion while patients in MDSI group were received with multiple daily subcutaneous injection of insulin every day.The blood glucose levels,length of stay,total insulin amount per day,the rate of hypoglycemia and the total effective rate of skin grafting were all recorded.Results: There were no differences in blood glucose(capillary blood glucose)levels at any time points before treatment between two groups.Both MDSI and CSⅡ treatment may cause significantly improved blood glucose levels.Compared with those of MDSI patients,patients under CSⅡ treatment may achieve even better glucose levels,more reduced rate of hypoglycemia,reduced length of stay and total amount of insulin per day(P<0.05).The ratio of successful skin grafting is also higher in CSⅡ group(P<0.05).Conclusion: CSⅡ therapy may achieve better blood glucose control,improve ratio of successful skin grafting and reduce the length of stay in burn patients with diabetes.