| Objective: To study The distribution of TCM Syndromes of type 2 diabetes with depress ion and anxiety,analyze the relationship between the TCM syndrome and insulin resistance a nd beta cell function.Methods:collected in accordance with the inclusion criteria of 169 cases of patients with type 2 diabetes,according to whether patients with depression and anxiety were divided into observation group of 52 cases and 117 cases in the control group.In the case of the four diagn ostic methods,bianzhengfenxing;simultaneous recording of the general project,including: ag e,height,weight,and body mass index(BMI),course of disease and degree of education;coll ect test index in patients with fasting blood glucose(FBG),Haemoglobin A1C(HbA1c),high sensitive C reactive protein(Hs-CRP)and other related indicators;fasting insulin value(FIN S),fasting C-Peptide values(FC-P),insulin sensitivity index(ISI)with HOMA formula,insul in resistance index(HOMA-IR),pancreatic beta] cell function index(HOMA-β),recorded Ha milton depression and anxiety rating scale(HAMD,HAMA);SPSS20.0 statistical software w as used for statistical analysis to analyze the relationship between TCM syndrome type and in sulin resistance and islet cell function.Result:1.The two groups of patients were statistically significant in terms of gender,age,and duration of the course,which is not statistically significant,all P>0.05,and the body ma ss index was statistically significant,P < 0.05;2.Observation group(with depression,anxiety group)and control group(without depression,anxiety),fasting insulin(FINS),insulin resistan ce index(HOMA IR)and islet beta cells secrete index(HOMA-β),insulin sensitive index(I SI),triglycerides(TG)was statistically significant difference(P < 0.05);3.According to the da ta of the two groups of patients,the TCM syndromes of the combined observation group(acc ompanied by depression and anxiety group)were obtained: liver depression qi syndrome,live r depression and stomach heat syndrome,and qi Yin deficiency syndrome.The TCM syndrom es of the control group(non-associated depression and anxiety group)were: phlegm fever,spl een syndrome,lung and stomach injury syndrome,and qi Yin deficiency syndrome.Through the analysis of symptoms and syndrome factors,the main clinical manifestations of patients w ith onset of type 2 diabetes mellitus with depression and anxiety disorders were emotional dep ression,body tired weakness,irritability,thirst like drinking,eating more easy hunger,dry mo uth,bitter,tightness in the chest,a bulge,five upset hot;From the analysis of the syndrome ele ments,the dialectical factors of qi and blood are mainly characterized by qi stagnation,qi ast henia and Yin deficiency,and the pathological products are both endogenous dryness and blood stasis.Viscera differentiation of the lesion in liver;The main clinical symptoms of patients with type 2 diabetes mellitus,which were not accompanied by depression and anxiety group,were mainly oral dry drink,body fatigue,frequent urination frequency,and five upset heat.A ccording to the dialectical analysis of qi and blood,the main syndromes of the syndrome are q i deficiency,Yin deficiency and pathological products,which are hot,phlegm and blood stasis,and the main lesion of the viscera is mainly in the spleen;4.Observation group of TCM syndr ome and insulin resistance and islet beta cell function and course of multiple classification log istics regression analysis found that: liver depression and qi stagnation syndrome,liver stomac h heat results are of course the OR value is less than 1,HOMA IR,HOMA-β OR value is grea ter than 1,and P < 0.05,suggesting that HOMA IR,HOMA-beta was positively correlated w ith various TCM syndrome types,and negatively correlated with course of the disease.Conclusion:(1)Newly type 2 diabetes patients with depression amd anxiety is given priority to with normal weight or angular,islet β cell function recession more apparent,insulin resistance,ins ulin sensitivity acceptable;In the early stage,patients with type 2 diabetes were mainly obese,insulin resistance was more severe,insulin sensitivity was poor,and the function of islet β cel ls was still available(2)Newly type 2 diabetes mellitus with depression,anxiety of TCM syndrome types as fo llows: the liver depression and qi stagnation syndrome,liver stomach heat,qi and Yin deficie ncy syndrome;Insulin resistance and islet β cell function in liver depression and qi stagnation-liver and stomach’s hotness-qi and Yin deficiency syndrome in the order is reduced,the cou rse with liver depression and qi stagnation-liver depression and stomach heat syndrome-qi a nd Yin deficiency syndrome in the order;For patients with primary type 2 diabetes mellitus with depression and anxiety group,the liver was the main issue,while the spleen was mainly f or the patients with primary type 2 diabetes. |
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