The Drug Therapy And Prognosis Of Children Atrial Tachycardia

Objective : To evaluate the drug therapy effects and prognosis of pediatric atrial tachycardia.Method:We collected the clinical datas of 109 atrial tachycardia cases that we treated with antiarrhythmic drug,at Children Hospital of Chongqing Medical University from January 2005 to December 2016.Divided into heart diseases group(congenital heart disease/cardiomyopathy/myocarditis)and no heart disease group,we discussed drug therapy efficacy and follow-up outcomes of each groups.Results:109 children with 62 cases of male,the female 47 cases,the onset age of AT occurred at birth~ 13.4(3.7 2.5)years.The most first visiting reason was respiratory tract infection.Compare the maximum heart rate recorded by ECG before and after treatment,there wws statistically significant differences(P < 0.01).There were no statistically significant differences in CK-MB,cTnI and LVEF(P > 0.05).The digitalis andβ-blocker showed highest effective rate in myocarditis group,and the digitalis in no heart disease group.There were no statistically significantdifferences in drug effects of congenital heart disease or cardiomyopathy group(P>0.05).47 cases were followed up regularly,the follow-up term was 10~73(32.4±15.3)months.The effective rate of myocarditis or no heart disease group was higher,younger children higher than the older,and there were statistically significant differences(P < 0.05).Three children who showed poor response to antiarrhythmic drugs had been controlled effectively through radiofrequency ablation.Conclusion:The digitalis showed significant effects in AT children without heart disease,and digitalis and β-blocker had significant control in myocarditis group.Most children who treated with antiarrhythmic drug resulted in good prognosis,especially in myocarditis group,no heart disease group and younger children.RFA should be considered for children who displayed poor response to medical therapy.