Comparison Of Nasal High-flow Oxygen Humidification And Noninvasive Ventilator In Treating AECOPD Combined With Respiratory Failure

Objective:Acute Exacerbation of Chronic Obstructive Pulmonary Disease(AECOPD)is a clinically common disease type.For the treatment of COPD,besides the routine basic treatment,it is also necessary to actively provide assistance in the improvement of patients with assisted ventilation.Oxygenation,reduce carbon dioxide retention,correct respiratory failure symptoms.The purpose of this study was to compare the efficacy of high flow nasal cannula(HFNC)and non-invasive positive pressure ventilation(NIPPV)in patients with AECOPD and type ? respiratory failure and to analyze their effect on AECOPD.The clinical application value of combined type ? respiratory failure aims to provide a reliable theoretical basis and data support for the clinical treatment of AECOPD combined with type ? respiratory failure.Methods: According to the 2015 edition of the “COPD Guidelines”(GOLD Guidelines),a total of 268 patients with AECOPD combined with type ? respiratory failure who were hospitalized in the Department of Respiratory Medicine of Harisen International Peace Hospital between December 2016 and January 2018 were selected.As a research object,105 patients met the inclusion criteria and exclusion criteria.After the screening,75 patients were included in the study.Informed consent was signed and the general conditions such as gender and age were recorded.Randomized digital tables were used to classify the subjects into nasal high flow group(HFNC group,38 cases)and non-invasive ventilation group(NIPPV group,37 cases).The HFNC group was given a nasal high flow treatment on the basis of conventional treatment;the NIPPV group was given non-invasive positive pressure ventilation on the basis of conventional treatment,and finally by comparing the two groups of patients before treatment,2 hours after treatment,6 hours after treatment,after treatment Oxygen saturation,oxygenation index,arterial blood pH,arterial blood oxygen partial pressure,arterial blood carbon dioxide partial pressure,respiratory rate,and heart rate after 12 hours and 24 hours after treatment were compared between the two groups after treatment.The number of airway nursing interventions,the intubation rate during hospitalization,mortality,and length of stay in hospitals were used to count the clinical efficacy and disease outcomes of the two groups.Results: 1.Patients in the HFNC and NIPPV groups were admitted to hospital for gender,age,arterial blood pH,arterial oxygen partial pressure(PaO2),arterial carbon dioxide tension(PaCO2),and oxygen saturation(Oxygen Saturation,SpO2),Oxygenation Index(PaO2/FiO2),acute physiology and chronic health evaluation(APACHE?),Breathing Rate(RR),heart rate(Heart There was no significant difference between Rat,HR,pulmonary function,and Use of Hormone(P>0.05).The two groups were comparable.2.Comparison of SPO2,Pa O2,PH,PaO2/FiO2,PaCO2,RR,HR before and after treatment,2 hours after treatment,6 hours after treatment,12 hours after treatment,and 24 hours after treatment in HFNC and NIPPV groups Changes,after comparison,no difference between the two groups,no statistical significance(P> 0.05).3.Comparison of the number of airway nursing interventions within 24 hours after treatment in the HFNC and NIPPV groups: After comparison,the HFNC group was significantly lower than the NIPPV group,and there was a difference between the two groups(P<0.05).4Compared the intubation rate,mortality rate and length of stay of the patients in the HFNC and NIPPV groups during hospitalization,there was no difference between the two groups(P>0.05).Conclusion: 1.AECOPD in patients with type ? respiratory failure(PaCO2 <70 mmHg without oxygen).There was no significant difference in efficacy between the HFNC group and the NIPPV group.2.AECOPD patients with type ? respiratory failure(PaCO2 <70 mmHg without oxygen).The number of airway nursing interventions within the HFNC group was significantly less than the NIPPV group within 24 hours after treatment.3.AECOPD patients with type ? respiratory failure(PaCO2 <70mmHg,no oxygen),HFNC group and NIPPV group had no significant difference in hospitalization time,intubation rate,and mortality rate during hospitalization.