The Relevant Of Abdominal Obese Woman In First-trimester And Gestational Diabetes Mellitus In Mid-trimester

Objective: To assess whether maternal abdominal adiposity in early pregnancy in Chinese population is associated with a higher risk of gestational diabetes mellitus(GDM)at a later gestational stage,ultrasound was used to measure the central adipose of pregnant women in early pregnancy.Methods: A total of 180 participants were scanned on a Philips iU22(Philips Medical Systems,USA)ultrasound machine with a 5-12 MHz probe.We measured women’s subcutaneous superficial adipose tissue(SSAT),subcutaneous deep adipose tissue(SDAT),visceral adipose tissue(VAT),and total adipose tissue(TAT)adipose tissue depth using ultrasound at 11–14 weeks’ gestation.A 75-g oral glucose tolerance test(OGTT)was performed between 24 and 28 weeks’ gestation.The risk of having a positive GDM,based on a 75-g OGTT at 24-28 weeks,was determined in association with SSAT,SDAT,VAT and TAT depths above their respective upper-quartile values relative to their bottom three quartile values.Results: 1.SDAT and VAT depths above the upper quartile value were significantly related with a positive GDM in mid-pregnancy in Chinese Population.The adjusted odd ratio(a OR)of SDAT and VAT was 8.9(95% CI 2.71-15.41)and 12.4(95% CI 3.15-19.90)respectively.2.TAT depth above the upper quartile values was moderately related with a positive GDM in mid-pregnancy(a OR 3.1,95% CI 0.75-7.09).3.No significant associations were seen for SSAT depth(a OR 1.1,95% CI 0.53-2.53).Conclusions: Increased first-trimester depths of SDAT,VAT and TAT independently predicted the risk of GDM in later pregnancy in Chinese population,especially;the increased first-trimester depths of SDAT strongly predicted the risk of GDM in later pregnancy.