Association Between Body Mass Index And Brachial-Ankle Pulse Wave Velocity

Objectives To evaluate the association between body mass index(BMI)and brachial-ankle pulse wave velocity(baPWV).Methods A total of 22681 Kailuan Group workers who participated in 2010-2011(2010),2012-2013(2012),2014-2015(2014)health examination and received baPWV measurement were included as the research subject.3625 participants were excluded from the lack of height and weight data and abnormality in ankle brachial index.Then,there were 19057 individuals finally included in the statistical analysis.According to the body mass index(BMI),subjects were divided into three groups:the normal weight group(BMI<24 kg/m~2),the overweight group(24 kg/m~2≤BMI<28 kg/m~2)and the obese group(BMI≥28 kg/m~2).The multivariate Logistic regression model was used to analyze the effect of different groups of BMI and an increase in a standard deviation of BMI on the ba PWV≥14 m/s.Results The prevalences of baPWV≥14 m/s in different BMI groups were 48.4%,60.7%and 63.8%respectively.After adjusting for confounding factors such as age,gender,the risk of baPWV≥14 m/s increased with the increase of BMI.However,when going on adjusting for mean arterial pressure(MAP),heart rate,smoking,drinking and physical exercise,hypertension,diabetes mellitus,dyslipidemia and other confounding factors,the multivariate Logistic regression analysis showed that the OR(95%CI)were 0.95(0.87~1.03)and 0.83(0.75~0.93)respectively for baPWV≥14 m/s in overweight ang obese group compared to normal BMI group;and as BMI increased a standard deviation,the OR(95%CI)was 0.93(0.90~0.97).Conclusions In the general population,BMI is not a good indicator for evaluating ba PWV.