Analysis Of Preterm Premature Rupture Of The Membranes And Analysis Of Pregnancy Outcomes

Objective: To analyze the pregnancy outcome and clinical management of PPROM at different gestational weeks.Methods: A total of 218 patients with PPROM admitted from the First Affiliated Hospital of Soochow University from July 2015 to June 2017 were enrolled in this study.Retrospective and comparative study was conducted in 24 patients(group A,28-31 + 6 weeks),49 cases(group B)in 32 ~ 33 + 6 weeks,and 145 cases in 34 ~ 36 + 6 weeks(group C).The general situation,complication rate,expectation time,mode of delivery and neonatal outcome of each group were compared,and the etiology of PPROM was analyzed.Results:(1)There was no significant difference between the three groups in age and parity(P> 0.05).The proportion of miscarriage ≥ 2 times,mean gestational age and pregnancy rate were statistically significant(P <0.05).The incidence of postpartum hemorrhage and puerperal infection in the three groups was not statistically significant(P> 0.05),and the incidence of amniotic cavity infection,placental abruption and oligohydramnios were statistically significant(P <0.05)In group C,the incidence of amniotic infection and placental abruption in group A was significantly increased(P <0.05).Compared with group C,the incidence of oligohydramnios in group B was significantly increased(P <0.05).(3)Compared with group B and group C,expectant time of group A was significantly longer(P <0.05),group B was significantly longer than group C(P <0.05)).(4)There was no statistically significant difference in 1min asphyxia rate and 5min asphyxia rate among the three groups(P>0.05).(5)The birth weight,Apgar 1min score,Apgar 5min score and neonatal infection rate were statistically significant(P<0.05).Compared with group B and group C,birth weight of group A was significantly lower(P<0.05),neonatal infection rate was significantly increased(P<0.05),and Apgar 1min score and Apgar 5min score of group A and B were not statistically significant(P>0.05).P>0.05),but significantly lower than that in group C(P<0.05).(6)The amniotic infection and cesarean section of the three groups were statistically significant(P<0.05).Compared with the incubation period <24h and 24-48 h,the amniotic cavity infection rate and cesarean section rate were significantly increased(P>0.05).<0.05).【Conclusion】Combination of reproductive tract infections,multiple abortions,increased intrauterine pressure,and scarred uterus are the main causes of PPROM.The smaller the gestational age of PPROM patients,the worse the maternal and child outcomes.For different gestational age PPROM patients should take different treatment strategies to assess the relative risk of preterm delivery and latency to prolong gestational age and focus on maternal and child safety.