Analysis Of Cervical Cancer Screening In 3 Years:Results For 1204 Married Women Of Childbearing Age In Binhai

Objective Through analyzing the incidence of cervical lesions in the county of Binhai in Jiangsu province for three consecutive years,to evaluate the clinical value and related factors of using liquid based thinprep cytologic test(TCT)and high-risk HPV-DNA test combined with colposcope cervical multipoint biopsying and pathology diagnosising in screening cervical intraepithelial neoplasia and cervical cancer,to improve the probability of early diagnosis and treatment and to the reduce mortality.Method Carrying out cervical cancer screening programme on the 18 to 25 years old women who have married,at the child-bearing age and will to accept screening in Binhai every six months during January 2009 to December 2011.All of them are screened by TCT first,the TCT results who are ASCUS(atypical「squamous cells of undetermined significance)should do the HPV-DNA tests,and both of them positive cases should be examined by colposcope and cervical biopsy.Results In 2009,the total number of cases are 1204,the abnormal rate of TCT was 6.31%,and let them to accept colposcopy and cervical biopsy.The results showed that the morbidity rate of CIN was 4.15%,and the rate of low-risk lesions(CIN Ⅰ)was 2.57%,the rate of high-risk lesions(CIN Ⅱ and above)was 1.58%.In 2010,the total number of cases are 1183,the abnormal rate of TCT was 3.55%,the morbidity rate of CIN was 2.28%,and the rate of low-risk lesions was 1.27%,the rate of high-risk lesions was 1.01%.In 2011,the total number of cases are 1110,the abnormal rate of TCT was 2.79%,the morbidity rate of CIN was 1.44%,and the rate of low-risk lesions was 1.08%,the rate of high-risk lesions was 0.36%.There was no cervical cancer cases in the 3 years.Conclusion TCT and high-risk HPV-DNA test combined with colposcope cervical multipoint biopsying and pathology diagnosising is an effective cervical screening test.Carring out the cervical cancer screening can discovery,diagnosis,treat CIN much earlier,in order to reduce the incidence of cervical cancer.