Synthesis And Properties Of Diarylethene Sensors Based On Hydrazide

In recent years,with the rapid development of society,it has caused numbers of pollution to the environment.Among them,ion pollution is very serious.Fluorescent probe detection technology plays an important role in the chemical and biological fields,which has received much attention.Fluorescent probes have been widely used in various fields such as chemistry and biology due to their excellent advantages such as short response time,high specificity,and low detection limit.On the other hand,in many photochromic materials,diarylethylene derivatives have superior properties over other photochromic materials,including fast response,excellent thermal stability,and good fatigue resistance.Based on this,many diarylethene derivatives have been used for ion detection by introducing some specific functional groups,which not only can respond to UV and visible light but also has response to other external stimuli such as pH,cations,anions and amino acids.In general,we introduce some specific functional groups on diarylethylene derivatives and they not only enriche the properties of diarylethene derivatives but also enable the detection of ions.The main content of this paper is as follows:In chapter 1,we mainly introduced the basic properties of diarylethene compounds,the composition and classification of fluorescent chemical sensors,the research progress and application of diarylfluorosensors.Finally,we put forward the content of this dissertation.In chapter 2-3,we synthesized DC-1 and DC-2 compounds which all based on 8-hydroxyquinoline fluorophores.After research,we found that the compounds DC-1and DC-2 not only had good photochromic properties,but also can specifically detect Cu²⁺.On the other side,compound DC-1 can detect CN^-through three methods.The first was colorimetric detection of CN^-.When CN^-was added to the solution of DC-1,the color of the solution will change significantly.The second was fluorescence detection of CN^-.The fluorescence was significantly enhanced and was not interfered by other anions after adding CN^-to the solution of DC-1.Thirdly,the fluorescence intensity reached a maximum value after adding the Cu²⁺to the solution of DC-1.But,the fluorescence intensity would decreases when we continually added CN^-in solution.So,we can also detect CN^-by this new method.In chapter 4,we synthesized DC-3 and DC-4 compounds which based on2,4-dihydroxybenzoyl fluorophore.For research,we found the two compounds can detect different metal ions.DC-3 and DC-4 can specifically detect Zn²⁺and Al³⁺repectivly.In addition,compound DC-3 can also detect Zn²⁺by colorimetric method.We also studied the complexation mechanism of compound DC-3 with Zn²⁺by means of NMR and mass spectrometry.Finally,we successfully used compound DC-3 to stain HeLa cells.Therefore,the experimental results show that the compound DC-3has a good application prospect and a certain research value.