| Background:Obesity is a chronic metabolic disease characterized by excessive accumulation of fat.It is caused by multiple factors.In recent years,the incidence of obesity has increased dramatically,making it a new global health problem and significantly increasing the medical burden.The treatment of obesity by traditional Chinese medicine is a hot research direction,and electro acupuncture therapy shows high effectiveness.But in the literature,the frequency of electro acupuncture treatment is different,and its effect on the curative effect is unknown.Objective:Objective to evaluate the efficacy and safety of electroacupuncture at different frequencies in the treatment of obesity.MethodThe trial was prospective,randomized,and two parallel control.A total of 120 obese patients were randomly allocated to 3 times/week electroacupuncture group and 1 times weekly electroacupuncture group.The two groups were taken as points:RN12,RN9,RN4,ST25,LI11,SJ9,ST44,ST40,ST37,SP9 and SP6.The two groups were treated for 4 weeks and followed up for 12 weeks.The main outcome index was the value of body weight change at the end of the treatment,and the secondary outcome index was the waistline,the hip circumference,the quality of life score,the compliance,and the safety evaluation.Results1.the value of body weight change:after the treatment,the weight change of the 3/week electroacupuncture group was-1.97 + 2.87kg,and the weight change of 1 times/week electroacupuncture group was-0.51 + 2.74kg,and the difference was statistically significant(P<0.05).Weight loss 5%;3 times/week,electro acupuncture treatment group was 11,1 times/week electroacupuncture treatment group was 2,the difference was statistically significant(P<0.05).After 12 weeks of follow-up,the weight change of the 3/week electroacupuncture group was-2,95 + 4.21kg,and the weight change of 1 times/week electroacupuncture group was-1.11 + 3.42kg,and the difference was statistically significant(P<0.05).Weight loss 5%:3 times/week,electro acupuncture treatment group was 8,1 times/week electroacupuncture treatment group was 5,the difference was statistically significant(P<0.05).2.the change value of the waist circumference:after the treatment,the waist circumference change of the 3/week electroacupuncture group was-2.79 + 3.59cm,and the waist circumference change of 1 times/week electroacupuncture group was-1.15 + 3.40cm,and the difference was statistically significant(P<0.05).After 12 weeks of follow-up,the waist circumference change of the 3/week electroacupuncture group was-4.42 + 5.74cm,and the waist circumference change of 1 times/week electroacupuncture group was-2.18 + 4.49cm,and the difference was statistically significant(P<0.05).3.the change value of hip circumference:after the end of the treatment,the hip circumference change of the 3/week electroacupuncture group was-1.05 + 2.15cm,and the hip circumference change of 1 times/week electroacupuncture group was-0.83 + 2.77cm,and the difference was not statistically significant(P>0.05).After 12 weeks of follow-up,the hip circumference change of the 3/week electroacupuncture group was-1.26 + 2.91cm,and the hip circumference change of 1 times/week electroacupuncture group was-1.01 + 5.83cm,and the difference was not statistically significant(P>0.05).4.SF-36:after the treatment,the value change of the SF-36 total score in the 3/week electroacupuncture group was 5.14 + 7.22,and the value change of the 1/week electroacupuncture group was 3.53 + 8.93,and the difference was statistically significant.There was no significant difference between the two groups(P>0.05).After treatment,there was no statistically significant difference between the two groups(P>0.05).After the two groups,the differences in PF,RP,GH,VT,and HT were statistically significant compared with before treatment(P<0.05);BP,SF,RE,and MH were different from those before treatment.There were statistical significance(P>0.05).After 12 weeks of follow-up,the values change of the SF-36 total score in the 3/week electroacupuncture group were-1.43 + 9.31,and the values change of the 1 times/week electroacupuncture group were 1.33 + 10.73,and the difference was statistically significant.There was no significant difference between the two groups(P>0.05).After 12 weeks of follow-up,there was no statistically significant difference between the groups in all dimensions(P>0.05).After 12 weeks of follow-up,the differences in PF,RP,GH,VT,and HT were statistically significant(P<0.05)compared with before treatment(P<0.05);BP,SF,RE,MH were poor compared with before treatment.The difference was not statistically significant(P>0.05).5.,safety and compliance:there was no significant difference in safety and compliance between the two groups(P>0.05),and no serious adverse events occurred.Conclusion:The effect of electroacupuncture at 3 times for 1 weeks is better than 1 weeks and 1 times,and the value of weight reduction,weight loss 5%and waist circumference reduction are better than 1 weeks 1 times in 3 times of electroacupuncture at 1 weeks.Whether the higher the frequency of acupuncture is,the better the weight loss effect is.More high-quality and large sample clinical trials are needed.Trial registration:AMCTR-IPR-17000057... |
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