Retrospective Study Of PiCCO To Monitor Shock Resuscitation And Myocardial Damage With Large Area Burn Patients In Early Stage

Objective: To investigate the effects of PiCCO to monitor shock resuscitation and myocardial damage with large area burn patients in early stage.Methods: A retrospective analysis of the Gansu Provincial People’s Hospital Burn Department 52 cases medical records of large area burn patients,whose were admitted within November 2015 to November 2017.According to different resuscitation monitoring methods,the patients were divided into traditional monitoring methods(control group)and PiCCO monitoring(PiCCO group).Among them,27 patients are resuscitated by conventional monitoring methods and other 25 cases are resuscitated using PiCCO.We collected all cases’ actual resuscitation volume in the first two days after burn,and the level of lactate,BE,NT-proBNP and cTn T in admission time to the seventh day after injury.Results: 1.The baseline data in PiCCO monitoring group and conventional monitoring group has no significant statistical difference(P> 0.05),there is no significant statistical difference in lactate,BE,NT-proBNP and cTnT between the two groups at admission time(P> 0.05).So it is reasonable to consider two groups were comparable at admission.2.The difference of the first 24 hours actual resuscitation between the two groups was statistically significant(P <0.05).There is no significant statistical difference in the second 24 hours actual resuscitation between the two groups(P> 0.05).3.After the first day’ resuscitation,the level of lactate and BE were improved in both two groups,and there was a significant difference between the two groups at the end of the first day(P <0.05),in addition,the difference was more significant in PiCCO group(P <0.01),and both of the differences after the first 24 h resuscitation treatment were statistically significant(P <0.05).4.There was no significant difference of lactate in admission between two groups(P> 0.05).The difference of lactate between two groups within first week after injury was statistically significant(P <0.05).5.There were significant differences of BE between the two groups on the 1st,2nd,3rd,6th and 7th days after injury(P <0.05),while on the 4th,5th days after injury,there was no significant difference of BE between the two groups(P> 0.05).6.The difference of NT-proBNP on the 1st,2nd,4th,5th,6th and 7th days after burn between two groups was statistically significant(P <0.05),while on admission time and the 3rd days after burn,there was no significant difference of the NT-pro BNP between the two groups(P> 0.05).7.The difference of cTn T on the 1st,2nd,6th and 7th day after burn between two groups was statistically significant(P <0.05),while on admission time and the 3rd,4th,5th days after burn,there was no significant difference of the cTn T between the two groups.(P> 0.05).Conclusion: Using PiCCO to monitor liquid therapy of large area burn patients in early stage is more reasonable,the alleviation effects of shock and myocardial damage is better than traditional monitoring methods.