The Clinical Analysis Of 130 Patients With Diffuse Lung Disease

Objective: To summarize the clinical data of patients with diffuse lung disease(DLD),to understand the distribution of DLD spectrum in our department,to summarize the clinical features of DLD patients,in order to improve the understanding of DLD and the level of dia gnosis and treatment,as the regional epidemiology information provided.Methods: A retrospective study of the department of respiratory and critical care medicine,general hospital of Ningxia medical university,from Januar y 2016 to December 2016,was conducted on the basis of the characteristics of hospitalized patients with DLD characteristics,including general conditions,clinical manifestation,examination,diagnosis,and treatment.Results: Of the 130 patients with DLD,71 were males and 59 were females.The male to female ratio was 1.2:1.The patients mainly in middle-aged and old-aged.According to the disease composition ratio,infectious disease(33.8),idiopathic interstitial pneumonia(IIP)(19.2%),connective tissue disease(CTD)(13.1%),malignant tumor(3.1%),exogenous allergic alveolitis(1.5%),drugrelated,diffuse panbronchiolitis,alveolar proteinosis were 0.8% each,and the remaining 26.9% of the patients were not diagnosed clinically.More than 80% of patients had cough,sputum,progressive dyspnea,and 79.5% had hypoxemia,but those things are not specific to diagnosis.Fever,fatigue,and weight loss are more common in infectious disease,and Velcro voice is dominated by IIP and CTD.Patients in the IIP and CTD groups had more visits than the infectious disease group.According to the incidence of chest CT according to the top three signs of the phenomenon of ground glass density,lobular septal thickening,patchy shadow.In the IIP and CTD groups,the incidence of lobular septal thickening,grid-like shadows,and traction bronchiectasis was higher than that of the infectious disease group.IIP had a higher incidence of cellular shadows than infectious diseases,whereas the latter had nodule-like,the incidence of shadow is higher.Lung biopsy was performed in 4 of 130 patients(3.1%),of whom 2 were confirmed(50%).98.5% of patients were treated with anti-infective therapy and antibiotic use rate was high.60.8% of patients were treated with glucocorticoids,and the use rate of the clinical diagnosis was unclear,IIP and CTD patients was higher.After treatment,101 patients(77.7%)had improved symptoms,27 patients(20.8%)had worsening symptoms or died,and 2 patients refused treatment for personal reasons.Conclusion: 1.Infectious diseases,IIP and CTD are common in this study,and 26.9% of clinical diagnoses are unclear.It is necessary to further improve the diagnostic level.2.Patients with short duration of illness,fever,fatigue,weight loss,and nodules were considered to be infectious diseases.For long course of disease,with velcro voice,interlobular septal thickening,grid-like shadow,traction bronchiectasis as the main patient,more consideration IIP or CTD-related lung involvement.3.The use of antibacterial and hormones in this study is high,and rationalization of treatment needs to be improved.