The Relationship Between Blood Lipid Level And VitD Level In Tibetan And Han Populations In Plateau

Objective:Dyslipidemia is an independent factor in the occurrence of cardiovascular events.There is a certain relationship between vitamin D deficiency and abnormal blood lipid metabolism;this study was to observe the clinical significance of the differences in blood lipid levels and vitamin D concentrations between Tibetan and Han nationality in the plateau region in order to develop cardiovascular disease in high altitude areas.Disease prevention methods provide scientific theoretical basis.Methods:From December 2016 to October 2017 In the Tibetan Plateau Gangcha area(3300m above sea level),Han population were randomly selected from 301 epidemiological survey data of ordinary adults by cross-sectional method to determine the indicators of biochemical lipid and its application Chemiluminescence Detection of Human Serum Vitamin D Concentration.All the data were processed by SPSS21.0 statistical software,and the relationship between serum 25(OH)D levels and physical examinations and clinical biochemical indexes was analyzed by binary Logistic regression.Results: 1.Vitamin D deficiency exists in the plateau area,among which the Tibetan vitamin D deficiency rate is 77.3%(male 70.3%,female 83.75%);the Han vitamin D deficiency rate is 61.9%(male 54.05%,female 69.7%),P <0.05;2.According to sex and ethnic group,the level of vitamin D in female Han is higher than that of Tibetan(16.88 vs 13.99,P = 0.014);The level of TC,TG,HDL-C was higher in Tibetan Han(P = 0.016)than in Tibetan(16.82 vs 16.24,P = 0.032);Han Chinese were Lower in TC,TG and LDL-C than in Tibetan(P <0.05)Higher than Tibetan(P <0.05);3.The TC,TG,and LDL-C levels in the vitamin D-deficient group were significantly higher than those in the Han population(P<0.05);the HDL-C levels were significantly lower than those in the Han population(P<0.05);the vitamin D deficiency group had no TC,TG,and LDL-C All of them were significantly higher than those of Han nationality(P<0.05),while HDL-C was significantly lower than Han nationality(P<0.05).4.Binary Logistic regression analysis was used to evaluate the effects of sex,blood lipids(TC,TG,HDL-C,and LDL-C)on vitamin D levels.Sex,TG,and LDL-C are risk factors for vitamin D deficiency in Tibetan and Han people;and TC is arisk factor for vitamin D deficiency in Tibetans;HDL-C is a protective factor for vitamin D deficiency in Tibetan and Han people.Conclusion: 1.The study suggests that the rate of vitamin D deficiency among Tibetans in the plateau area is 77.3%;the vitamin D deficiency rate in Han population is 61.9%.2.The dyslipidemia metabolism is the risk of vitamin D deficiency in Tibetan and Han populations.