The Effect Of Coronary Bifurcation Angle On Vascular Fluid Hemodynamics As Well As Plaque Formation And Distribution

The coronary artery is a series of blood vessels wrapped on the surface of the heart with geometry features,such as bifurcation,bending,deformation,and shrinkage cone.Because of the complexity of geometric structure and the deformation of heart,being internal contraction and diastole,a series of dynamic characteristics have brought about a great influence on the dynamics of blood flow.Abnormal blood flow is an important factor causing the pathological changes of vessel wall.The study of hemodynamics of coronary artery includes the distribution of blood flow field,the features of high pressure and low shear stress.Therefore,obtaining accurate mechanical parameters of individual flow of left coronary artery is very important for prediction and location of atherosclerotic plaque.It is also an important basis for clinical study of plaque formation,development and rupture movement.In this paper,we establish ideal coronary artery models and patient-specific models with different bifurcation angles,create the control conditions and boundary conditions(including inlet and outlet conditions and wall conditions)that meet the human body function,to apply computationalfluid dynamics(CFD)methods in the interest of comparing and analyzing the hemodynamic characteristics of different bifurcation angle models,summarizing the relationship between bifurcation angle and atherosclerosis,providing a theoretical basis for clinical diagnosis and treatment of atherosclerosis,bring some reference for the relationship between bifurcation angle and atherosclerosis.