Clinical Efficacy Observation Of Yiqi Huoxue Prescription In Treating Coronary Heart Disease After PCI

Purpose: To observe the clinical efficacy and safety of Yiqi Huoxue Prescription in the treatment of coronary heart disease patients with qi deficiency and blood stasis syndrome on the basis of conventional western medicine,explore the effective prescriptions of Chinese medicine for the treatment of Qi deficiency and blood stasis syndrome after PCI,and optimize the use of syndrome differentiation drugs.Method: This study was selected from 140 patients with qi deficiency and blood stasis syndrome who met the diagnostic criteria in the outpatient department of cardiology at the Affiliated Hospital of Gansu University of Traditional Chinese Medicine from January 2017 to January 2018.They were randomly divided into control group and Observation group.The control group was treated with conventional Western medicine,and the observation group was treated with Yiqi Huoxue Prescription on the basis of the treatment of the control group for 15 days.Observe the efficacy of TCM syndrome before and after treatment,the effect of angina pectoris,the reduction of nitroglycerin,ECG efficacy,low-density lipoprotein,left ventricular ejection fraction,6-minute walking test,and European V dimension health scale visual analogue scale(EQ-VAS))Improvements in scores were analyzed using SPSS 23.0 software.Chi-square test was performed on the count data.Measured data were expressed as mean ±standard deviation(?X2±S).The t-test was used.Rank data were used for the rank sum test to evaluate Clinical Effect of Yiqi Huoxue Prescription in Treating Qi Deficiency and Blood Stasis Syndrome after PCI.Result:(1)Efficacy of TCM syndromes: The total effective rate of the observation group after treatment was 80.6%,and that of the control group was 29.4%.There was statistically significant difference between the two groups(P<0.001);(2)Angina pectoris efficacy: The total effective rate of the observation group after treatment was 81.9% The control group was 55.9%,and the difference was statistically significant(P<0.01).(3)The nitroglycerin reduction rate: The total effective rate was 88.9% in the observation group and 66.2% in the control group after treatment.There was a significant difference between the groups.Statistical significance(P<0.01);(4)Efficacy of ECG: The total effective rate of the observation group after treatment was 72.2%,and the total effective rate of the control group was 50%.The difference was statistically significant(P<0.05);(5)The LDL-c Effects: There was no difference between the observation group and the control group after treatment(P>0.05);(6)Effect on left ventricular ejection fraction(LVEF): There was a significant difference in improvement of LVEF between the observation group and the control group after treatment(P<0.001);(7)Effects on the 6-minute walking test: There was no significant difference between the observation group and the control group after treatment(P>0.05);(8)Effect on the EQ-VAS score of the European Five-Dimensional Health Scale: observation group and control group after treatment There was significant statistical significance(P<0.001).Conclusions: The use of Yiqi Huoxue Prescription in this study not only significantly improve the TCM syndromes of patients with qi deficiency and blood stasis syndrome,relieve angina pectoris,increase the rate of nitroglycerin reduction,improve the efficacy of electrocardiogram,improve LVEF,and increase the visual analogue scale of European five-dimensional health scale.(EQ-VAS)score,but no significant improvement in LDL-c and 6MWD,the overall efficacy was definite,and no adverse reactions were found.