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The Clinical Observation Acupoint Embedding On Leflunomide Induced Leukopenia In Rheumatoid Arthritis

Posted on:2019-04-29Degree:MasterType:Thesis
Country:ChinaCandidate:J J TuFull Text:PDF
GTID:2334330545983222Subject:Acupuncture and massage to learn
Abstract/Summary:PDF Full Text Request
Objective:Through the observation of clinical cases,the observation of acupoint embedding for patients with hepatic and renal deficiency rheumatoid arthritis.The effects of joint function,laboratory parameters and acupoint embedding on the treatment of rheumatoid arthritis.Research methods:1.Clinical data: All 60 patients were from June 2016 to June 2017 Wuhan Traditional Chinese Medicine Hospital Wet Pain Clinic,All people met the diagnostic criteria for hepatic and renal deficiency rheumatoid arthritis.The 60 RA patients were numbered 1,3,and 5 according to the order in which they sought medical treatment......59 points into the control group(alone for the fluomide group),2,4,6......60 points into the treatment group(acupoint embedding combined with the use of fluomide group);30 cases per group.2.Treatment methods:For 30 cases taken alone in the fluomet group(control group),the fluomide was taken in accordance with the instructions of Leflomide.Two tablets per day were taken orally for 12 weeks.Acupoint buried line combined with oral levomide group(treatment group)in 30 cases,on the basis of the control group with the use of acupoint buried wire,twice a week to perform a acupoint buried wire,six weeks for a course of treatment,12 weeks of treatment.When the patient suffers from joint pain during treatment,according to the patient’s condition,the patient can take oral sodium Luosuoluofen tablets(1-3 times a day,one piece at a time)as appropriate,when the patient’s joint pain is reduced or relieved.When the patient can tolerate,Stop oral Luosuoluofen sodium tablets.In addition to this,do not take any other drugs related to the disease.3.Observing targets: Clinical symptoms and signs: morning stiffness duration,resting pain,degree of joint dysfunction,number and degree of joint pain and swelling,average grip strength of both hands,visual simulation scale(VAS),patient evaluation,disease activity score(doctor),HAQ index,DAS 28;Arthrographic Imaging: Main Observation of Two Hand X-ray Images;Laboratory Indicators: Rheumatoid Factor,Hematocele,C-reactive Protein,CCP.4.Statistical methods:Using SPSS 19.0 software package for statistical processing analysis,the measurement data were measured by mean + standard deviation(x RIs),the matching T test was compared among the groups,the two independent samples T test were compared among the groups,the count data was measured by X2,the rating data was determined by ridit,the statistical data was denoted by X ±S,the difference was statistically significant with P < 0.05.Results:1.The two groups of patients(a total of 60 cases)took the drug under the guidance of the doctor,and the doctor completed the insertion of acupuncture points.In the control group and the treatment group,30 cases each,all patients completed all the treatment well.No one stopped taking drugs or did not take acupoint wire treatment during the course of treatment.There were no cases of removal,shedding,etc..2.The clinical efficacy of the two groups of patients before and after 12 weeks of treatment was compared: the effective rate was 83 % in the control group and 91 % in the treatment group.After comparison,the difference was statistically significant(P<0.05),and the therapeutic effect of the treatment group was better than that of the control group.3.There was no significant difference in the statistical analysis between the two groups of patients with joint function(P > 0.05).After 12 weeks of treatment,these values were compared.After statistical analysis,the difference was statistically significant(P<0.05),indicating that both groups could effectively improve the joint function of the patient.4.The clinical efficacy of the two groups of patients before and after 12 weeks of treatment was compared: the effective rate was 83 % in the control group and 91 % in the treatment group.After comparison,the difference was statistically significant(P<0.05),and the therapeutic effect of the treatment group was better than that of the control group.Comparing RF,ESR,and CRP data before treatment in each group,the statistical analysis has no statistical significance(P > 0.05)and is comparable;After 12 weeks of treatment,these values were compared,and after statistical analysis,the difference was statistically significant(P<0.05).There was a significant difference between the pre-treatment and post-treatment data in the group(P<0.05).It shows that the laboratory indexes of rheumatoid arthritis patients have a certain control effect,and for reducing these laboratory indexes,the control effect of laboratory indexes is better when used together with acupoint embedding lines.Conclusion:1.Combined with leflomide,the acupoint embedding can significantly improve the joint function and laboratory index of patients with hepatic and renal deficiency rheumatoid arthritis.2.The combined effect of acupoint embedding and oral levomide on rheumatoid arthritis was better than that of simple oral levomide.3.Acupoint embedding combined with oral levomide can improve the joint function of patients with rheumatoid arthritis more than oral levomide alone.
Keywords/Search Tags:Rheumatoid arthritis, Leflunomide, acupoint catgut embedding, Liver and Kidney Deficiency Type
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