Clinical Observation On Chronic Obstructive Pulmonary Disease Treated By Invigorating Lung And Tonifying Kidney

Objective:By invigorating the lung and tonifying the kidney method combined with Seretide(Salmeterol fluticasone inhaler,British GlaxoSmithKline)on the treatment of patients with chronic obstructive pulmonary disease with deficiency of qi and kidney,and the effects of their ventilation function,dyspnea,acute exacerbation times,quality of life and deficiency of lung and kidney,To verify the mechanism and effectiveness of invigorating lung and tonifying kidney,and to provide more extensive theoretical basis and practical experience for the treatment of chronic obstructive pulmonary disease by TCM and WM.Method:Sorting out 60 cases of hospitalization and outpatient Department of TCM Hospital of Wuhan City from November 2015 to November 2016,the selected patients need to conform to the diagnostic criteria of 2013 GOLD chronic obstructive pulmonary disease guideline and the clinical diagnostic criteria of TCM "Lung distension" syndrome syndrome of lung-qi deficiency.60 patients were divided into treatment group and control group by random Digital table method,and Seretide(50ug/500ug)inhaled ≥ 16 weeks,and 30 patients with basic therapy,such as smoking cessation,oxygen therapy,pulmonary function exercise and enhanced nutritional support,were selected as control group.,on the basis of the control group,the treatment group was set up with 30 patients who were treated with lung tonifying kidney syndrome and the time ≥ 16 weeks.The age of the two groups before entering the clinical observation stage,there was no significant difference in statistics between sex,severity of disease,disease course,pulmonary function grading,quality of life,dyspnea,lung and Kidney deficiency(p>0.05),analysis of the duration of follow-up,severity of course,Pulmonary ventilation function,dyspnea,lung and kidney deficiency symptom remission,quality of life assessment scale data,and treatment 1 years after the acute exacerbation times.Results:1.Lung function Evaluation: After the treatment,the two groups of patients with lung function FEV1 estimated value and FEV1/FVC than before treatment,there is a certain degree of increase,before and after treatment p<0.01,there is significant statistical significance of the two groups of patients compared,the treatment group of patients with FEV1 estimated value and fev1/ FVC was higher than the control group,p<0.05,there were significant differences,and the results were statistically significant.2.Degree of remission of dyspnea symptoms: After the treatment,the mMRC grading of the two groups was decreased(p<0.05)compared to the treatment,with comparable significance,the comparison between the two groups of patients,the treatment group of patients with the mMRC grade compared to the control group significantly lower,the difference is statistically significant(p<0.05).3.Lung and kidney deficiency symptom improvement score: After the treatment,the two groups of patients with lung and kidney Qi deficiency symptom score is lower than before treatment,and the treatment group symptom score than before treatment significantly reduced,p<0.01,the difference is statistically significant,the control group score than before treatment slightly lower,p>0.05,the difference is not statistically significant;After the treatment,the two groups of patients were compared with each other,the treatment group of patients with lung and kidney deficiency symptom score compared to the control group has a significant reduction trend,the difference is statistically significant(p<0.05).4.Quality of life Assessment: After the treatment,the two groups of patients with cat score compared to the treatment before all have a certain reduction,the difference is statistically significant(p<0.05),the two groups of comparison,the treatment group cat score compared to the control group decreased more significantly,has significant statistical significance(p<0.01).5.Acute exacerbation: After the treatment,the two groups of patients with acute exacerbation of the number compared to before treatment were reduced,has a statistical significance(p<0.05),the two groups of contrast,the treatment group of acute exacerbation times significantly less than the control group of acute exacerbation,p< 0.01,it is suggested that the difference between the two is statistically significant.Conclusion:Treatment of patients with chronic obstructive pulmonary disease in stable stage by supplementing lung and tonifying kidney method combined with Seretide improve the patient’s lung ventilation function,reduce the number of patients with acute exacerbation,improve the quality of life of patients,easing the patient’s waist and knees limp,low sound of qi,chest tightness Damba,such as lung and kidney qi deficiency symptoms.The combination of traditional Chinese and Western medicine treatment can be more accurate dialectical,aimed at patients with individual specific drug treatment,improve clinical efficacy and quality of life of patients.