Clinical Study Of Early Enteral Nutrition Support In Severe Burn Patients

Objective:To explore the value of early enteral nutrition in the treatment of severe burn patients.Methods:A multicenter retrospective study was done on 52 severe burn patients who are hospitalized in three hospitals(Suzhou Municipal Hospital,First Affiliated Hospital of Suzhou University and Second Affiliated Hospital of Suzhou University)in Suzhou from august to September in 2014.According to starting time,they are divided into early enteral nutrition group(EEN group,n=28)and non-early enteral nutrition group(NEEN group,n=24).To compare the amount of intake energy to object energy,the amount of enteral and parenteral nutrient intake to total energy respectively when two group patients are burned from 1st to 7th day,at 14th day,21st day and 28th day.And also,to compare scores of Acute physiology and chronic health evaluation(APACHE Ⅱ),prealbumin,creatinine,urea nitrogen when two group patients are treated at 3rd day,7th day,14th day,28th day,primary operation time in 28 days and operation numbers as clinical data.Results:EEN group were given enteral nutrition within 48 hours after admission.NEEN group was given enteral nutrition within 48h to 72h after admission.The first parenteral nutrition implementation time in the two groups was 24～48h.In 7 days,their total intake energy was both lower than object energy,and EEN group was much lower.At 14th day,21st day and 28th day,their total intake energy was both meet object needed energy.And increase trend of EEN group was much stable.Their enteral nutrient intake was roughly equal to parenteral nutrient intake from 96h after admission,and took enteral way as first in 7 days.After treatment,scores of APACHE II were both improved,and scores of two group patients at 3rd day,7th day,14th day,and 28th day were both better than hospitalized in ICU(P<0.05).Scores of APACHE II for EEN group at 7th day,14th day,and 28th day were better than NEEN group.Prealbumin numbers for EEN group at 28th day were better than NEEN group(P<0.05).And creatinine,urea nitrogen at 3rd day,7th day,14th day,28th day,primary operation time in 28 days and total operation numbers for two group patients had no statistical differences.Also,the incidence of enteral nutrient adverse reaction for two group patients had no statistical differences.Conclusions:Using early enteral nutrition in therapies for severe burn patients possesses several benefits:it can make energy intake more stably,reduce disease severity of patients,improve plasma prealbumin levels at 28th day,and it does not increase the incidence of adverse reaction.