Analysis Of Epidemiological History,clinical Symptoms And Laboratory Test Results Of 80 Cases Of Imported Malaria In Hefei

Objective: To understand the epidemiological data,clinical treatment and laboratory indicators of 80 imported malaria cases in Hefei area,and to provide fundamental statistics for disease prevention,clinical diagnosis,treatment and prognosis evaluation of imported malaria.Method: By retrospective method,information of a total of 80 definited diagnosed imported malaria cases from 2015 to 2017 was collected,including epidemiological data,clinical feature,laboratory detection of Plasmodium falciparum,blood routine,biochemical indicators,then 100 healthy subjects were recruited as control group for statistical analysis.Results: African countries are the mainly high-prevalence area for imported malaria,and the most infected cases are found in Angola,followed by Congo.The majority of infected cases is young adults who are working abroad,and the clinical symptoms in the early stage of disease are characterized as fever,chill and sweating.Comparing to the control group of 100 healthy subjects,the WBC,E%,PLT,RBC and HB in 80 imported malaria cases were reduced,while N% and B% were elevated;in biochemistry examination,ALT,AST,TB,DB,IB,BUN and CR and were elevated,while TP and UA were reduced.The differences between two groups were statistically significant(p<0.05);indicated by binary logistic regression analysis,higher value of N%,ALT or TB resulted in higher possibility of developing malaria;lower value of HB or PLT also led to higher possibility of developing malaria.Conclusion: The clinical symptoms are complex and various.Laboratory indicators in patients and healthy subjects were different,and obvious significance was found in HB and PLT reduction as well as N%,ALT and TB elevation,which was of certain referential value in early diagnosis and treatment for imported malaria.