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Efficacy Of Arsenic Trioxide Drug-eluting Stents In The Treatment Of Coronary Heart Disease

Posted on:2017-09-11Degree:MasterType:Thesis
Country:ChinaCandidate:S S ZhangFull Text:PDF
GTID:2334330536471802Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective:The study aim was to evaluate the safety and clinical efficacy of arsenic trioxide drug-eluting(AVI)stents,manufactured in China,in the treatment of patients with coronary heart disease(CHD).Methods: From January to August in 2014,40 patients with CHD in our hospital with implanted AVI stents alone were selected.A 1-year clinical follow-up was completed,and 1-year postoperative coronary angiography was reviewed.Major adverse cardiovascular events(MACE),recurrent angina,stent restenosis,and stent thrombosis cases were observed.MACE including cardiac death,target lesion revascularization,nonfatal myocardial infarction.Results:All 40 CHD patients completed 1-year clinical follow-up,as well as 1-year postoperative coronary angiography.The follow-up results showed that the MACE rate was 15.0%(6/40),the target lesion revascularization rate was 15.0%(6/40),there were no cases of cardiac death or nonfatal myocardial infarction,the angina recurrence rate was 32.5%(13/40),the in-stent restenosis rate was 20.0%(8/40),and the stent thrombosis rate was 0.Conclusion:The incidence of restenosis after implantation of AVI stent was higher,and the safety and clinical efficacy were worse than expected.
Keywords/Search Tags:drug-eluting stent, arsenic trioxide, percutaneous coronary intervention
PDF Full Text Request
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