The Comparison Of The Pulmonary Function Between Sub-pulmonary Lobectomy And Pulmonary Lobectomy

Objective: To evaluate the feasibility of thoracoscopic lobectomy in the treatment of lung diseases by summarizing the clinical data of patients undergoing thoracoscopic lobectomy and sub-lobectomy.,Safety and surgical indications,the next step in the development of sub-lobectomy to provide the necessary theoretical basis and scientific experimental data.Methods: A total of 120 patients underwent thoracoscopic subtotal laryngectomy and thoracoscopic lobectomy from June 2015 to June 2016 were divided into two groups according to the different surgical methods.The patients were divided into lobectomy group Cases and sub-lobectomy in 52 cases.The patients underwent conventional laboratory tests(blood routine,urine,liver and kidney function,coagulation function,blood gas analysis,tumor markers,etc.),bronchoscopy,respiratory function,abdominal B ultrasound,lung ECT,head MRI,Upper abdomen CT,whole body ECT scan,or systemic PET / CT examination to exclude distant metastases.There were no significant differences in FEV1%,FVC,MVV% and blood gas analysis indexes Pa O2 and Pa CO2 between sex and preoperative pulmonary function.The changes of lung function were compared between the two groups in the perioperative period,10 days and 3 months after operation.The observed indexes included FEV1%,FVC%,MVV%,Pa O2 and Pa CO2.Results: The age,sex,smoking history,previous history,operation time,intraoperative blood loss,postoperative hospital stay,postoperative drainage time and operation-related complications were compared between the two groups.The results showed that the age,There were significant differences(P <0.05)in postoperative closed drainage time> 48 h,postoperative complications(atelectasis,left heart failure,hemothorax)and so on.There were no significant differences in gender,smoking history,past medical history,operation time,intraoperative blood loss and postoperative hospital stay,and there was no significant difference between thoracoscopic lobectomy group and sub-lobectomy group.The results showed that the FEV1%,FVC% and MVV% of the two groups were not statistically significant(p> 0.05).The two groups of patients had no significant difference in lung function between the two groups(P> 0.05)The FEV1%,FVC% and MVV% of the patients were significantly lower than those before operation(p <0.05).The FEV1% of patients undergoing thoracoscopic subtotal lobectomy was significantly higher than that of thoracoscopy(P <0.05).However,there was no significant difference in FVC% and MVV% between the two groups(p> 0.05),but there was no significant difference between the two groups(p> 0.05).The Pa O2 and Pa CO2 values were compared between the two groups before and after operation.The results showed that there was no significant difference in the blood gas analysis between the two groups(p> 0.05).There was no significant difference between the two groups(P <0.05),while Pa CO2 had no significant difference(P> 0.05).There was no significant difference in Pa O2 and Pa CO2 between the two groups on the 7th day after operation,No statistically significant(p> 0.05).Conclusion: Sub-lobectomy is a safe and effective treatment for non-small cell lung cancer in the treatment stage.Sub-lobectomy can achieve the same effect as lobectomy and can preserve more normal lung tissue and reduce postoperative complications Disease,postoperative quality of life improved significantly.