| ObjectiveTo investigate the effect of GFR on short-term clinical outcomes in patients with with chronic cardiac insufficiency.MethodsFrom December 2015 to June 2016,choose 101 cases of patients with chronic cardiac insufficiency,inspection theblood biochemical(serum creatinine,blood urea nitrogen levelsincluded)after admission when patients are fasting state,and other indicators,parallel cardiac ultrasound measure its ejection fraction(EF)and related indicators.According to the formula of Cockcroft e GFR numerical calculation.In accordance with the level of GFR were divided into group a :GFR ≥90 ml/(min.1.73m~2)and group b 45ml/(min.1.73m~2)≤GFR<90ml/(min.1.73m~2),two groups of cases of 45 cases,56 cases respectively.All of the patients by the medical standard treatment after the middle of the back function improvement(NYHA class I)discharged from hospital.After hospital discharge the patient were followed up for 6 months,according to the patient follow-up whether cardiovascular adverse events happened during the period of 6 months,the patients in events to specific groups and the two groups.Cardiovascular adverse events including death(cardiovascular)and hospitalization for heart failure increased again.Application of statistical software SPSS 17.0 statistical data analysis,with P < 0.05 for the difference was statistically significant.Results1.In group a,there have 38 cases did not end point events,a total of 7 cases of end point event happened,calculated the finish incident rate was 15.55%,and group b,there have 37 cases of no end point events,end point event happened(19 cases),calculated the incidence of end point events was 33.93%,increased incidence of group b is a set of events,prompt GFR mild-to-moderate lower than normal group increased the probability of a finish event,difference(don’t)have statistical significance(x2 = 4.406,p < 0.05).2.Event group GFR 71.396 + /-18.786ml/(min.1.73m~2),the event group GFR83.513 + /-14.337ml/(min.1.73m~2),the event group GFR value is less than the event group(P < 0.05).Tip: according to the results of the Pearson correlation analysis,left ventricular ejection fraction(LVEF)and GFR are positively correlated,r = 0.674,p< 0.05,this suggests that within a certain range,the higher the GFR,left ventricular ejection fraction(LVEF)is larger.3.To analyze the multiple regression equation to left ventricular ejection fraction as the dependent variable,Age,GFR,Scr,BUN as independent variables,the multivariate stepwise regression analysis,GFR eventually entered the regression model,it shows that in patients with chronic cardiac insufficiency,GFR is an independent factors affecting ejection fraction.GFR decline in patients with risk of cardiovascular adverse events in the near future.4.GFR predict chronic cardiac insufficiency prognosis(survival)of ROC curve six months,the area under the curve(AUC)0.754(95% ci: 0.637 0.871).To best boundary value GFR = 45.6 ml/(min.1.73m~2)to predict chronic cardiac insufficiency patients for half a year the happening of cardiovascular events.Conclusion1.Glomerular filtration rate(GFR)patients with mild-to-moderate decline in the glomerular filtration rate(GFR)normal in patients with chronic cardiac insufficiency,the increased incidence of vascular events within six months.2.The left ventricular ejection fraction and glomerular filtration rate were positively correlated,a certain range,the glomerular filtration rate increases,left ventricular ejection fraction increased.3.GFR is used to predict the half year prognosis of patients with chronic cardiac insufficiency value of 45.6ml/(min.1.73m~2)... |
PDF Full Text Request