The Clinical Value Of PCT For The Identification Of Bacterial Infection Sites And Strains

Objective: Through the statistical analysis of the relationship between procalcitonin(PCT)and the infection sites and pathogens,pct detection in the diagnosis of clinical value of systemic infection and local infection and clinical application value of the pathogen identification,in order to provide accurate clinical observation data for clinical timely and reasonable drug treatment.Methods: the serum PCT and bacterial culture results of 158 patients with bacterial infection in emergency intensive care unit were studied retrospectively,and the results of PCT examination in 24 hours with bacterial culture were selected.Compare the PCT level of systemic infection and local infection and the difference of serum PCT level between Gram-negative and gram positive bacteria,finally draw the roc curve to determine the optimal pct cut-off value of systemic infection and local infection and the best pct cut-off value.Results: 1.PCT in the systemic infection group was(17.54)ng / ml,compared with the local infection group(3.98)ng / ml,the difference was significant(p < 0.01),the highest value of PCT was 0.233,the sensitivity was 64.5%,the specificity was 58.8%.2.PCT in the G-infection group(22.18)ng / ml,compared with G+ infection group(8.26)ng / ml increased significantly,the difference between the two groups was significant(p < 0.01).the highest value of PCT was 4.96 ng / ml,the sensitivity was 87.5%,the specificity was 72.3%3.PCT has no significant difference in the local infection group(4.39)ng / ml with G-and G+ infection group(p =0.09).4.PCT analyzed the level of respiratory system infection(4.42)ng / ml,urinary system infection(3.89)ng / ml,nervous(2.35)ng / ml,and found no significant difference(p = 0.15)Conclusion : 1.PCT increased more obviously in systemic infection,compared with local infection,PCT can identify the systemic body and local infection.2.PCT increased significantly in the group of G-systemic infection,compared with G+ infection group,there was significant difference,PCT can identify the systemic infection of G-and G+ infection.3.PCT has no significant difference between G-and G+ in local infection.PCT on the level of PCT in respiratory tract urinary and nervous system infection,found that there was no significant difference between the three.PCT can not distinguish the local infection site,nor the local infection.