The Value Of T2~*Weighted Magnetic Resonance Imaging In The Diagnosis Of Myocardial Lesions In Patients With Subclinical Type 2 Diabetes Mellitus

Objective:To research the effect of different gender and age groups on the T2* value of normal left ventricular segments.Methods:35 subjects with normal heart were enrolled in the study,included 20 males and 15 females,which were divided into young group(≤44,n=10),middle-aged group(45~59,n=15)and the elderly group(over 60 years old,n=10).The T2* values of the 16 segments of the left ventricle were measured by 3.0T CMR 8 echoes T2*WI sequence.The differences between different gender and age groups were compared by using Independent sample t test and one-way ANOVA.Results:The T2 star value of the left ventricular anterior basal segment(2segments)(28.23±3.51ms)of the male group is lower than the female group(32.79±6.44ms),the difference was statistically significant(P<0.05);the T2*value of the left ventricular apical segment(13 segments)of normal young people(34.02±5.89ms)was higher than that of normal middle-aged subjects(27.62±4.18ms),and higher than the normal elderly(27.34±4.79ms),the differences were both statistically significant(P<0.05).Conclusions: There was a gender difference in T2 star values of the normal left ventricular basal anteroseptal(2 segments)measured in this study,and the anterior wall of left ventricular apex(13 segments)in the normal young people,the elderly;the rest of the myocardial segments T2* value had no significant difference in gender and age.Objective:To investigate the diagnostic value of T2* weighted imaging in myocardial lesions of the subclinical type 2 diabetes mellitus.Methods: 22 cases were collected in our hospital clinical diagnosis of subclinical stage in patients with type 2 diabetes,including 12 males,10 females,mean age 48±2.5 years(age range 47-60 years),the first part included 15 middle-aged healthy subjects as normal control group,there were8 males and 7 females,the average age of 50±3.5 years(age range 46-58years).All subjects underwent routine scan and cardiac T2* weighted scan;The left ventricular cardiac function indexes(LVMI,EDVI,ESVI,SVI,CI,MVR,PFR,PER)and the T2* values of the 16 segments of the left ventricle,and the correlation between the parameters of left ventricular function and analysis,the correlation between the T2* value and left ventricular function parameters was analyzed.Results:The T2* value of the left ventricular inferoseptal basal segment(3 segments)in subclinical type 2 diabetes mellitus group was lower than the normal control group,the difference was statistically significant(P<0.05).The LVMI,EDVI,ESVI and PER between the subclinical type 2 diabetes mellitus group and the control group was no statistically significant(P<0.05),the SVI,CI,EF and PFR of type 2 diabetes mellitus group were lower than the control group,the difference was statistically significant(P<0.05),the MVR of type 2 diabetes mellitus group was higher than thecontrol group,the difference was statistically significant(P<0.05).There was no correlation between the T2* value of the left ventricular basal segment and the cardiac function index of the left ventricular(P<0.05).Conclusions: The T2* value of the left ventricular inferoseptal basal segment(3 segments)in subclinical type 2 diabetes mellitus reduced,while reduced left ventricular diastolic function,left ventricular systolic function did not changes significantly.It is suggested that the cardiac function of patients with type 2 diabetes mellitus is mainly due to impaired diastolic function.