Research Progress Of Protective Ventilation Strategy In Perioperative Period Of Lung Transplantation

At present,lung transplantation is a relatively mature program for the treatment of advanced lung disease,for more and more end-stage lung disease patients bring healthy gospel.However,the current lung transplantation development stagnation,the main reasons include:(1)in the traditional culture of deep-rooted and expensive cost of surgery in the background,the patient usually less than a last resort will not choose to lung transplantation,so as to miss the best timing of surgery;The number of donor lungs available for transplantation is not sufficient to meet clinical needs,and the mortality rate on the waiting list is as high as 22%.(3)Even if the patient undergoes a lung transplant,it may be due to early primary dysfunction,PGD),acute rejection(acute rejection),chronic rejection,infection and other serious complications and death.Mechanical ventilation plays a very important role in all stages of lung transplantation,but inappropriate mechanical ventilation may cause ventilator-associated lung injury.Pulmonary protective ventilation strategies include: low tidal volume ventilation,pulmonary resuscitation,permissible hypercapnia and relatively appropriate positive end expiratory pressure(PEEP).It plays an important role in preoperative management of recipient lung and lung transplant recipients,both during surgery,and in the management of postoperative lung transplantation,which has become a major strategy for perioperative ventilation in lung transplantation.In this paper,the literature review,lung protective ventilation strategy in lung transplantation in the perioperative study of the progress of a review..