| Objective:To analyze the related factors and risk factors of fracture in patients with type 2 diabetes mellitus,collecting the data of type 2 diabetic patients with fracture and type 2 diabetes patients.To reduce the risk of fracture in patients with type 2 diabetes,to ensure the safety of patients,improve the health level of patients,save social and economic costs.Method:In this study,cases and controls were matched by age and sex for 1:2.Sampling of 225 inpatients in a general hospital of Jiangxi from May 2016 to December 2016 by purposive sampling method in Nanchang: 75 fracture in patients with type 2 diabetes mellitus(case group)and 150 patients with type 2 diabetes mellitus(control group).The data of patients in the case group and the control group were collected,including the medical records,the results of biochemical tests,and the results of imaging examination;Body mass index was calculated according to the height and weight of the patients.Result:There were significant statistical differences in the duration of diabetes,cataract,smoking and calcium supplement between the cases and the control group(p<0.05),There were significant statistical differences in the living style,body mass index,serum alkaline phosphatase,previous history of fracture,cerebral infarction(p<0.01).Stepwise regression analysis finally entered the model with three variables: solitary,serum alkaline phosphatase and body mass index.The HR values of solitary,serum alkaline phosphatase and body mass index were: 2.79(95%CI: 1.39 ~ 5.63),1.01(95%CI: 1.00 ~ 1.01),0.88(95%CI: 0.81 ~ 0.96).Conclusion:Living alone,high serum alkaline phosphatase and low body mass index are risk factors for fracture in type 2 diabetes mellitus patients.Diabetes duration,cataract,smoking,supplemental calcium,non-living along,previous history of fracture,cerebral infarction are relative factors for fracture in patients with type 2 diabetes. |
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